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  1. ...phases of the cell cycle show generally broad expression in cells across the atlas, suggesting that a daughter-to-mother state transition is not explained easily by cell cycle activity (Supplemental Data Set S11). Indeed, cell cycle–related genes are not prominent among DEGs for any particular cluster...
  2. ...of Biology, St. Cloud State University, St. Cloud, Minnesota 56301, USA; 3Driver Group, LLC, San Francisco, California 94158, USA; 4BioTuring, Incorporated, San Diego, California 92121, USA; 5Department of Biochemistry, Stanford University, Stanford, California 94305, USA; 6California Institute...
  3. ...organisms, the six cas genes located directly adjacent to the cmr genes were conditionally regulated during growth (Fig. 3B). We speculate that this growth/physiologic state-associated preparedness against anticipated viral attack is a reflection of a Table 1. Summary of , transcriptome architecture...
  4. ...flux. The rate changes identified by our method are associated with microbial lifestyle changes such as transitions from generalist to host-restricted pathogen lifestyles. We have made a software implementation of the algorithm with a graphical interface freely available from http...
  5. ...the assembled contigs obtained in the Rickettsia pyrosequencing run with the 3-kb PCR product that frames the gyrA gene of the URFtCIPR strain, two contigs of 176 bp and 101 bp contained the gyrA sequence and the point mutation associated with quinolone resistance (C to T transition at position 524 of gyr...
  6. ...and Karlin 1998 ). One of the accepted hypotheses states that the potential cause of asymmetry is deamination of methylated cytosines, which leads to thymines. Some investigators believe that this type of substitution differentiates between sense and antisense strands of coding sequences, and transcription...
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