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  1. ...their localization. We previously described the generation of deletion complexes centered at the Dpp6, Hdh , and Gabrb1 loci using the technique of ES cell irradiation ( Schimenti et al. 2000 ). However, this collection contained a large gap between Hdh and an ES cell haplolethal locus, the deletion of which...
  2. ...resolution, assigning long-range interacting elements to their target genes genome-wide in embryonic stem cells and fetal liver cells. The distal sites contacting active genes are enriched in active histone modifications and transcription factor occupancy, whereas inactive genes contact distal sites...
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