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  1. ...rare, duplications were shortest and very common, and translocations occurred at a moderate frequency and size. Syntenic regions are distributed over the entire length of all chromosomes between all pairs; however, synteny has become highly fragmented by rearrangements and unaligned regions...
  2. ...for the speciation and adaptations such as mimicry (Joron et al. 2011; Hill et al. 2019; de Vos et al. 2020), mostly owing to reciprocal translocation and repeated events of fusion and fission among a highly dynamic number of chromosomes between species.To better understand the phenomenon of scrambling, we study...
  3. ..., defined as a karyotype that is not a multiple of the haploid complement, generates dosage imbalance among genes on different chromosomes (Birchler et al. 2001; Chen et al. 2019). Consistent with the balance hypothesis, aneuploidy often results in a more severe growth defect than polyploidy, which keeps...
  4. ...3 deposition, such as EZH2, KMT2 (MLL) family members, and KDM6A, are translocated or mutated and/or their expression is altered in many malignancies (Suvà et al. 2013; Dawson 2017). Such defects had been documented in a handful of studies. In detail, analyses in established prostate (Gal-Yam et al...
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