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Research: Fitness benefits of loss of heterozygosity in Saccharomyces hybrids
- Samuel M. Lancaster,
- Celia Payen,
- Caiti Smukowski Heil,
- and Maitreya J. Dunham
Genome Res. October 2019 29: 1685-1692; Published in Advance September 23, 2019, doi:10.1101/gr.245605.118
..., Caudy AA, Dunham MJ. 2019. Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species-dependent essential genes. Genome Res 29: 396–406. doi:10.1101/gr.232330.117 ↵Scannell DR, Frank AC, Conant GC, Byrne KP, Woolfit M, Wolfe KH. 2007. Independent sorting...
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Research: Independent evolution of transcript abundance and gene regulatory dynamics
- Gat Krieger,
- Offir Lupo,
- Avraham A. Levy,
- and Naama Barkai
Genome Res. July 2020 30: 1000-1011; Published in Advance July 22, 2020, doi:10.1101/gr.261537.120
...similarity of the hybrid alleles with one of the parents was surprising to us, because we expected that combining differentially regulated trans-acting factors within the same would result in additive or synergistic effects rather than dominant effects. Examining all trans-diverging genes, we found...

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