Searching journal content for articles similar to Sambrook et al. 15 (1): 25.

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  1. ...that recognize the major histocompatibility complex (MHC) Class I molecules expressed by other cells. For primate NK cells, the killer-cell immunoglobulin-like receptors (KIR) are a variable and rapidly evolving family of MHC Class I receptors. Studied here is KIR3DL1/S1 , which encodes receptors for highly...
  2. ...analogous functions. Humans preferentially use LRC-encoded KIR (killer cell immunoglobulin-like receptors) genes to engage nonclassical MHC Class I molecules, while rodents use NKC-encoded KLRA ( Ly49 ) genes for the same role. The functional homology of human KIR s and mouse KLRA genes is believed to have...
  3. ...histocompatibility complex (MHC) and the killer immunoglobulin-like receptor (KIR) cluster, have generally been rather poorly annotated, as evidenced by gaps and incorrect assemblies in several whole- sequencing projects covering various species other than humans (He et al. 2019; Warren et al. 2020; Jayakumar et al...
  4. ...of KRAB-ZNF genes. The tissue-specific expression patterns and rapid structural divergence of ZNF91 subfamily genes suggest a role in determining gene expression differences between species and the evolution of novel primate traits. Most genes are conserved as 1:1 orthologs in different mammalian species...
  5. ...Diego, La Jolla, California 92093, USA Abstract The chimpanzee genome sequence is a long-awaited milestone, providing opportunities to explore primate evolution and genetic contributions to human physiology and disease. Humans and chimpanzees shared a common ancestor ∼5-7 million years ago...
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