Searching journal content for articles similar to Salonen et al. 8 (7): 724.

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  1. METHODS: Gene Structure Prediction and Alternative Splicing Analysis Using Genomically Aligned ESTs
    • Zhengyan Kan,
    • Eric C. Rouchka,
    • Warren R. Gish,
    • and David J. States
    Genome Res. May 1, 2001 11: 889-900; doi:10.1101/gr.155001
    ...structures. Expressed sequence tags (ESTs), which are single sequencing reads from cDNA clones, provide a tremendous resource for gene identification. As of February 10, 2001, the dbEST database has nearly 3.2 million human ESTs and continues to grow rapidly. Several software tools have used the EST resource...
  2. RESEARCH: Minisequencing: A Specific Tool for DNA Analysis and Diagnostics on Oligonucleotide Arrays
    • Tomi Pastinen,
    • Ants Kurg,
    • Andres Metspalu,
    • Leena Peltonen,
    • and Ann-Christine Syvänen
    Genome Res. June 1, 1997 7: 606-614; doi:10.1101/gr.7.6.606
    ...and does not leave the 3′ end free for extension. High-density arrays have also been produced by chemical coupling of NH2-modified cDNAs as miniaturized spots on an activated glass surface using high-capacity printing robotics ( Schena et al. 1996 ). Arrays prepared by this technology could be used...
  3. METHODS: A System for Specific, High-throughput Genotyping by Allele-specific Primer Extension on Microarrays
    • Tomi Pastinen,
    • Mirja Raitio,
    • Katarina Lindroos,
    • Päivi Tainola,
    • Leena Peltonen,
    • and Ann-Christine Syvänen
    Genome Res. July 1, 2000 10: 1031-1042; doi:10.1101/gr.10.7.1031
    ...genes. The SNPs are planned to be used as markers in large-scale searches for genes underlying common, multifactorial diseases by linkage disequilibrium mapping or genetic association studies ( Schafer and Hawkins 1998 ; Collins et al. 1999 ). Functional SNPs in genes encoding drug-metabolizing enzymes...
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