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  1. .... A k-mer that is shared by two sequences implies an identical region of size k, and with appropriate length on k, we may detect similar but nonidentical regions through shared k-mers. Some of the reasons that k-mers are often used for sequence similarity detection is because they are fast to construct...
  2. ..., the number runs in the BWT grows sublinearly, as repetitive regions of the pan only extend existing runs rather than increase their number (Boucher et al. 2018; Kuhnle et al. 2020). The r-index addresses the space complexity of the FM-index by leveraging the pan's repetitiveness, similar to graph...
  3. ..., Hayes W, Hunt BR, Mount SM, Yorke JA. 2004. Reducing storage requirements for biological sequence comparison. Bioinformatics 20: 3363–3369. doi:10.1093/bioinformatics/bth408 ↵Sahlin K. 2021. Effective sequence similarity detection with strobemers. Genome Res 31: 2080–2094. doi:10.1101/gr.275648...
  4. ...in length with a ≤1% error rate. High-quality long reads have been used to accurately assemble s (Kolmogorov et al. 2019; Nurk et al. 2020; Ekim et al. 2021; Bankevich et al. 2022), complete the human (Nurk et al. 2022), accurately detect small variants in challenging genomic regions (Olson et al. 2022...
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