Searching journal content for articles similar to Ruby et al. 17 (12): 000.

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  1. ...in Drosophila melanogaster, much less is known about the origin and evolution of piCs in this or any other species. To investigate piC origin and evolution, we use a population genomic approach to compare piC activity and sequence composition across eight geographically distant strains of D. melanogaster...
  2. ...reveal miRNA diversity among Drosophila species and principles underlying their emergence and evolution.MicroRNAs (miRNAs) are an extensive class of ∼22-nt RNAs that play important regulatory roles in diverse eukaryotic species (Flynt and Lai 2008; Axtell et al. 2011). In the canonical metazoan pathway...
  3. ...of a substantially expanded set of Drosophila microRNAs. Genome Res 17: 1850–1864. Rutherford SL, Lindquist S. 1998. Hsp90 as a capacitor for morphological evolution. Nature 396: 336–342. Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. 2011. A ceRNAhypothesis: the Rosetta Stone of a hidden RNA language? Cell 146...
  4. ...types in human. However, high-level editing is mostly found in neuronal tissues in mouse and Drosophila. Interestingly, the edited miRNAs in neuronal and non-neuronal tissues in human gain two distinct sets of new targets, which are significantly associated with cognitive and organ developmental...
  5. ...cleavage. (A) Distribution of miRNA:mRNA alignment mismatch scores in Nematostella vectensis, Homo sapiens, Drosophila melanogaster, and Arabidopsis thaliana, shown as the difference in abundance between miRNAs and matching shuffledmiRNAs, counting the fraction of sequences in each set having a best match...
  6. ...of functional retrogenes in Drosophila. Genome Biol 8: R11. ↵Bartel DP. 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281–297. ↵Berezikov E, Liu N, Flynt AS, Hodges E, Rooks M, Hannon GJ, Lai EC. 2010. Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nat Genet 42...
  7. ...Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence Eugene Berezikov 1 , Nicolas Robine 2 , Anastasia Samsonova 3 , Jakub O. Westholm 2 , Ammar Naqvi 2 , Jui-Hung Hung...
  8. ...Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line Nelson C. Lau 1 , 2 , 6 , 7 , 8 , Nicolas Robine 3 , 6 , Raquel Martin 3 , Wei-Jen Chung 3 , Yuzo Niki 4 , Eugene Berezikov 5...
  9. ...of total RNA to investigate the relationships with microRNA target expression. We show microRNA maternal loading and sequence-specific 3′ end nontemplate oligoadenylation of maternally deposited microRNAs that is conserved between Tribolium and Drosophila . We further uncover large clusters encoding...
  10. ...differences in the set of predicted target genes. The novel predicted miRNAs lead to 37 novel miRNA families with unique 5′ seed sequences, doubling the number of miRNA families and, thus, the diversity of miRNA targeting in Drosophila . Our results also lead to several new insights into miRNA biology. We...
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