Searching journal content for articles similar to Ruault et al. 31 (3): 411.

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  1. ...that tethering of heterochromatic regions to nuclear landmarks and random encounters of chromosomes in the confined nuclear volume are sufficient to explain the higher-order organization of the budding yeast genome. We have quantitatively characterized the contact patterns and nuclear territories that emerge...
  2. ...mediated by chromosomes and nuclear proteins. Crowding is expected to screen out hydrodynamic effects, which otherwise induce long-range interactions in between chromosome segments (Doi and Edwards 1988), so that nearest-neighbor elastic interactions between consecutive chromosome segments dominate...
  3. ...such long-range interactions, we differentially tagged pairs of chromosome ends and developed an automated three-dimensional measuring tool that determines distances between two telomeres. In yeast, all chromosomal ends terminate in TG1–3 and middle repetitive elements, yet subgroups of telomeres also share...
  4. ...-enter the cell cycle upon sensing of external cues. Q cells are responsive to the environment and flexible enough to adapt to available resources. In budding yeast, quiescent nuclear features are drastically distinct from those observed in nutrient replete conditions: The nuclear volume is reduced; the telomeres...
  5. ...origins in yku80Δ, rif1Δ, sir2Δ, sir3Δ, and sir4Δwere defined within 50 kb from the telomeres (Methods). (C) Replication profile around centromeres. Shown are the replication profiles around the centromere (marked in a dashed red line) of Chromosome 16 for the indicated strains (green) compared...
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