Searching journal content for articles similar to Rossato et al. 33 (5): 787.

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  1. Perspective: Unraveling the hidden complexity of cancer through long-read sequencing
    • Qiuhui Li,
    • Ayse G. Keskus,
    • Justin Wagner,
    • Michal B. Izydorczyk,
    • Winston Timp,
    • Fritz J. Sedlazeck,
    • Alison P. Klein,
    • Justin M. Zook,
    • Mikhail Kolmogorov,
    • and Michael C. Schatz
    Genome Res. April 2025 35: 599-620; Published in Advance March 20, 2025, doi:10.1101/gr.280041.124
    ...number alterations, and some structural variants (SVs) (Choo et al. 2023). This high-throughput, cost-effective technology has facilitated large-scale cancer genomics projects like The Cancer Genome Atlas (TCGA) (The Cancer Genome Atlas Research Network et al. 2013), the International Cancer Genome...
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  2. Review: Leveraging the power of long reads for targeted sequencing
    • Shruti V. Iyer,
    • Sara Goodwin,
    • and William Richard McCombie
    Genome Res. November 2024 34: 1701-1718; doi:10.1101/gr.279168.124
    ...fragment length via hybridization, and it is extremely difficult, if not impossible, to accurately assemble DNA fragments <10 kb in regions like this.CRISPR-Cas9-based enzymatic targeting approachesThe CRISPR–Cas system provides a specific, rapid, and flexible enzymology (Jinek et al. 2012; Doudna...
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  3. Research: Genome-wide variability in recombination activity is associated with meiotic chromatin organization
    • Xiaofan Jin,
    • Geoff Fudenberg,
    • and Katherine S. Pollard
    Genome Res. September 2021 31: 1561-1572; Published in Advance July 23, 2021, doi:10.1101/gr.275358.121
    ..., spatially accessible genomic regions during meiotic prophase are associated with DSB-favored loci, which further adopt a transient locally active configuration in early prophase. Conversely, crossover formation is depleted among DSBs in spatially accessible regions during meiotic prophase, particularly...
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