Searching journal content for articles similar to Ronald et al. 15 (2): 284.

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  1. ...A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data Daniel A. Skelly 1 , 3 , Marnie Johansson 1 , Jennifer Madeoy 1 , Jon Wakefield 2 and Joshua M. Akey 1 , 3...
  2. ..., Uppsala University, 75185-Uppsala, Sweden Abstract This study describes a practical system that allows high-throughput genotyping of single nucleotide polymorphisms (SNPs) and detection of mutations by allele-specific extension on primer arrays. The method relies on the sequence...
  3. ...) Noise reduction from genotyping microarrays using probe level information . In Silico Biol. 6 : 9 . ↵ Laframboise, T. , Weir, B.A. , Zhao, X. , Beroukhim, R. , Li, C. , Harrington, D. , Sellers, W.R. , Meyerson, M. ( 2005 ) Allele-specific amplification in cancer revealed by SNP array analysis . PLo...
  4. ...-Density Oligonucleotide Arrays The high-density oligonucleotide array used to detect the mutations conferring rifampin resistance in M. tuberculosis was also used to simultaneously genotype and speciate nontuberculous isolates. As the interspecies sequence variation for the rpoB gene of some of the nontuberculous...
  5. ...gene, for 96 samples in parallel. The c D NA-mediated a nnealing, s election, extension and l igation (DASL) assay targets specific transcripts, using oligonucleotides containing unique address sequences that can hybridize to universal arrays. Cell-specific gene expression profiles were obtained...
  6. ...single nucleotide polymorphism genotyping and gene expression profiling. The algorithm requires only a few labels and several sequential hybridizations to identify thousands of different DNA sequences with great accuracy. We have decoded tens of thousands of arrays, each with 1520 sequences represented...
  7. ...reported differentially methylated genes ( Adorjan et al. 2002 ; Esteller 2002 ; Tsou et al. 2002 ). The assay procedure is similar to that described previously for standard SNP genotyping ( Fan et al. 2003 ), except that four oligonucleotides, two allele-specific oligonucleotides (ASOs), and two locus...
  8. ..., they have been used to identify and genotype single nucleotide polymorphisms ( Wang et al. 1998 ), monitor gene expression ( Lockhart et al. 1996 ), analyze genetic screens ( Shoemaker et al. 1996 ), design antisense oligonucleotides ( Milner et al. 1997 ), identify bacterial species ( Gingeras et al. 1998...
  9. ...that the minisequencing approach is more straight forward and specific for multiplex mutation detection on oligonucleotide arrays than hybridization with allele-specific probes. Here we describe a solid-phase minisequencing assay for nine disease-causing mutations in an oligonucleotide array format. The mutations were...
  10. ...and mutant oligonucleotides, resulting in a 4 × 5 matrix (Fig. 4 A). View this table: In this window In a new window Table 1. PCR Primers, Product Size (bp), and Array-Bound Allele-Specific Oligonucleotide Probes Used for Genotyping Results of target hybridization demonstrate ability to distinguish the three...
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