Searching journal content for articles similar to Robbins et al. 17 (12): 1717.

Displaying results 1-10 of 11

For checked items

view abstracts
download to citation manager

Select this article
Method: Genome-wide detection of natural selection in African Americans pre- and post-admixture
- Wenfei Jin,
- Shuhua Xu,
- Haifeng Wang,
- Yongguo Yu,
- Yiping Shen,
- Bailin Wu,
- and Li Jin
Genome Res. March 2012 22: 519-527; Published in Advance November 29, 2011, doi:10.1101/gr.124784.111
...components of ancestry in AfA and comparing it with indigenous African populations (IAF). Interestingly, many selection-candidate genes identified by the new approach were associated with AfA-specific high-risk diseases such as prostate cancer and hypertension, suggesting an important role these disease...
Select this article
Research: An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer
- Nora F. Wasserman,
- Ivy Aneas,
- and Marcelo A. Nobrega
Genome Res. September 2010 20: 1191-1197; Published in Advance July 13, 2010, doi:10.1101/gr.105361.110
...tumorigenesis occurs. With widely varying risk allele frequencies in different populations—from49% inAmericanCaucasians to 81% inAfrican Americans (HapMap, merged Phase 1, 2, and 3 frequencies)—this SNP may also have an effect on the population prevalence of both prostate cancer and colorectal cancer (Jemal et...
OPEN ACCESS ARTICLE
Select this article
Perspective: Unraveling the hidden complexity of cancer through long-read sequencing
- Qiuhui Li,
- Ayse G. Keskus,
- Justin Wagner,
- Michal B. Izydorczyk,
- Winston Timp,
- Fritz J. Sedlazeck,
- Alison P. Klein,
- Justin M. Zook,
- Mikhail Kolmogorov,
- and Michael C. Schatz
Genome Res. April 2025 35: 599-620; Published in Advance March 20, 2025, doi:10.1101/gr.280041.124
...in earlier studies (Gustafson et al. 2024; Schloissnig et al. 2024). One of the largest long-read projects to date is the All of Us Research Program, which has employed PacBio HiFi reads to sequence over 1000 African American samples in the phase I project (Mahmoud et al. 2024) and is progressing to over 10...
OPEN ACCESS ARTICLE
Select this article
Research: Actionable exomic incidental findings in 6503 participants: challenges of variant classification
- Laura M. Amendola,
- Michael O. Dorschner,
- Peggy D. Robertson,
- Joseph S. Salama,
- Ragan Hart,
- Brian H. Shirts,
- Mitzi L. Murray,
- Mari J. Tokita,
- Carlos J. Gallego,
- Daniel Seung Kim,
- James T. Bennett,
- David R. Crosslin,
- Jane Ranchalis,
- Kelly L. Jones,
- Elisabeth A. Rosenthal,
- Ella R. Jarvik,
- Andy Itsara,
- Emily H. Turner,
- Daniel S. Herman,
- Jennifer Schleit,
- Amber Burt,
- Seema M. Jamal,
- Jenica L. Abrudan,
- Andrew D. Johnson,
- Laura K. Conlin,
- Matthew C. Dulik,
- Avni Santani,
- Danielle R. Metterville,
- Melissa Kelly,
- Ann Katherine M. Foreman,
- Kristy Lee,
- Kent D. Taylor,
- Xiuqing Guo,
- Kristy Crooks,
- Lesli A. Kiedrowski,
- Leslie J. Raffel,
- Ora Gordon,
- Kalotina Machini,
- Robert J. Desnick,
- Leslie G. Biesecker,
- Steven A. Lubitz,
- Surabhi Mulchandani,
- Greg M. Cooper,
- Steven Joffe,
- C. Sue Richards,
- Yaoping Yang,
- Jerome I. Rotter,
- Stephen S. Rich,
- Christopher J. O’Donnell,
- Jonathan S. Berg,
- Nancy B. Spinner,
- James P. Evans,
- Stephanie M. Fullerton,
- Kathleen A. Leppig,
- Robin L. Bennett,
- Thomas Bird,
- Virginia P. Sybert,
- William M. Grady,
- Holly K. Tabor,
- Jerry H. Kim,
- Michael J. Bamshad,
- Benjamin Wilfond,
- Arno G. Motulsky,
- C. Ronald Scott,
- Colin C. Pritchard,
- Tom D. Walsh,
- Wylie Burke,
- Wendy H. Raskind,
- Peter Byers,
- Fuki M. Hisama,
- Heidi Rehm,
- Debbie A. Nickerson,
- and Gail P. Jarvik
Genome Res. March 2015 25: 305-315; Published in Advance January 30, 2015, doi:10.1101/gr.183483.114
...African ancestry) inDorschner et al. (2013) and 391 additional variants in the remaining 5503 (4300 European-ancestry and 2203 African-ancestry) participants. This is attributable to the most common variants being identified in the first set analyzed, leaving fewer novel variants in the second set...
OPEN ACCESS ARTICLE
Select this article
Perspective: Genetic architecture of quantitative traits in mice, flies, and humans
- Jonathan Flint and
- Trudy F.C. Mackay
Genome Res. May 2009 19: 723-733; doi:10.1101/gr.086660.108
...according to the experimental design. Suppose we identify a QTL that contributes to 1% of the genetic variation in an outbred population. In a model organism we could then set up a breeding program to isolate that chromosomal region so that all other genomic regions are inbred—consequently, the locus now...
Select this article
Research: Radiation pharmacogenomics: A genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines
- Nifang Niu,
- Yuxin Qin,
- Brooke L. Fridley,
- Junmei Hou,
- Krishna R. Kalari,
- Minjia Zhu,
- Tse-Yu Wu,
- Gregory D. Jenkins,
- Anthony Batzler,
- and Liewei Wang
Genome Res. November 2010 20: 1482-1492; Published in Advance October 5, 2010, doi:10.1101/gr.107672.110
...cytotoxicity dose-response curves. Two cell lines from each of the three ethnic groups studied were selected to illustrate a range of radiation cytotoxicity ‘‘dose response’’ curves. Squares indicate African-Americans (AA), triangles CaucasianAmericans (CA), and circles indicate Han Chinese–Americans (HCA...
Select this article
Research: HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter
- Mijke Visser,
- Manfred Kayser,
- and Robert-Jan Palstra
Genome Res. March 2012 22: 446-455; Published in Advance January 10, 2012, doi:10.1101/gr.128652.111
...-Saharan African genetic origin of the respective cell donors (Supplemental Fig. S1). Both data sets are in agreement with the light and dark skin-color phenotype informationof theHEMn-LP andHEMn-DP cell donors, as provided by Cascade Biologics. We investigated the transcription status of the OCA2 gene in our skin...
OPEN ACCESS ARTICLE
Select this article
ARTICLE: Pattern of Sequence Variation Across 213 Environmental Response Genes
- Robert J. Livingston,
- Andrew von Niederhausern,
- Anil G. Jegga,
- Dana C. Crawford,
- Christopher S. Carlson,
- Mark J. Rieder,
- Sivakumar Gowrisankar,
- Bruce J. Aronow,
- Robert B. Weiss,
- and Deborah A. Nickerson
Genome Res. October 2004 14: 1821-1831; Published in Advance September 13, 2004, doi:10.1101/gr.2730004
...that is representative of the ethnic diversity of the United States population (Coriell Institute; http://locus.umdnj.edu/nigms/products/pdr.html ). The panel includes 24 European, 24 Asian, 24 African, 12 Hispanic, and six Native American samples. PCR amplifications were performed in 96-well plates in a volume of 7 μ...
Select this article
Research: Extensive somatic L1 retrotransposition in colorectal tumors
- Szilvia Solyom,
- Adam D. Ewing,
- Eric P. Rahrmann,
- Tara Doucet,
- Heather H. Nelson,
- Michael B. Burns,
- Reuben S. Harris,
- David F. Sigmon,
- Alex Casella,
- Bracha Erlanger,
- Sarah Wheelan,
- Kyle R. Upton,
- Ruchi Shukla,
- Geoffrey J. Faulkner,
- David A. Largaespada,
- and Haig H. Kazazian, Jr.
Genome Res. December 2012 22: 2328-2338; Published in Advance September 11, 2012, doi:10.1101/gr.145235.112
...incidence of microsatellite instability in colorectal cancer from African Americans. Clin Cancer Res 9: 1112–1117. Babushok DV, Ostertag EM, Courtney CE, Choi JM, Kazazian HH Jr. 2006. L1 integration in a transgenic mouse model. Genome Res 16: 240– 250. Baillie JK, Barnett MW, Upton KR, Gerhardt DJ...
Select this article
PERSPECTIVE: The canine genome
- Elaine A. Ostrander and
- Robert K. Wayne
Genome Res. December 2005 15: 1706-1716; doi:10.1101/gr.3736605
...including dog, wolf, coyote, Ethiopian wolf or Simien jackal, and three other species of jackals (genus Canis ), as well as the African hunting dog (genus Lycaon ) and the dhole (genus Cuon ); and (3) the South American canids including fox-sized canids such as the pampus fox, crab-eating fox, and small...

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Robbins et al. 17 (12): 1717.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: