Searching journal content for articles similar to Risch and Teng 8 (12): 1273.

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  1. ARTICLE: The Relative Power of Family-Based and Case-Control Designs for Linkage Disequilibrium Studies of Complex Human Diseases. II. Individual Genotyping
    • Jun Teng and
    • Neil Risch
    Genome Res. March 1, 1999 9: 234-241; doi:10.1101/gr.9.3.234
    ...The Relative Power of Family-Based and Case-Control Designs for Linkage Disequilibrium Studies of Complex Human Diseases. II. Individual Genotyping Jun Teng 1 and Neil Risch 1 , 2 , 3 , 4 1Department of Statistics, Stanford University and Departments...
  2. Methods: Genome-wide comparisons of variation in linkage disequilibrium
    • Yik Y. Teo,
    • Andrew E. Fry,
    • Kanishka Bhattacharya,
    • Kerrin S. Small,
    • Dominic P. Kwiatkowski,
    • and Taane G. Clark
    Genome Res. October 2009 19: 1849-1860; Published in Advance June 18, 2009, doi:10.1101/gr.092189.109
    ...disequilibrium (LD) (de Bakker et al. 2006a). Powerful analytical tools have also utilized the comprehensive information from these databases to increase genomic coverage and fine-map association signals through statistical imputation of untyped genetic variants that exist in the databases (Marchini et al. 2007...
  3. RECOMB Special/Methods: Increasing power in association studies by using linkage disequilibrium structure and molecular function as prior information
    • Eleazar Eskin
    Genome Res. April 2008 18: 653-660; Published in Advance March 18, 2008, doi:10.1101/gr.072785.107
    ...Increasing power in association studies by using linkage disequilibrium structure and molecular function as prior information Eleazar Eskin 1 Departments of Computer Science and Human Genetics, University of California Los Angeles, Los Angeles, California 90095, USA...
  4. REVIEW: Linkage Disequilibrium and the Search for Complex Disease Genes
    • L.B. Jorde
    Genome Res. October 1, 2000 10: 1435-1444; doi:10.1101/gr.144500
    ...and substance dependence. Am. J. Hum. Genet. 65 : 599 – 605 . ↵ Risch N. , Merikangas K. ( 1996 ) The future of genetic studies of complex human diseases. Science 273 : 1516 – 1517 . ↵ Risch N. , Teng J. ( 1998 ) The relative power of family-based and case-control designs for linkage disequilibrium studies...
  5. METHODS: Genetic Analysis of Case/Control Data Using Estimated Haplotype Frequencies: Application to APOE Locus Variation and Alzheimer's Disease
    • Daniele Fallin,
    • Annick Cohen,
    • Laurent Essioux,
    • Ilya Chumakov,
    • Marta Blumenfeld,
    • Daniel Cohen,
    • and Nicholas J. Schork
    Genome Res. January 1, 2001 11: 143-151; doi:10.1101/gr.148401
    .... Hum. Genet. 64 : 1147 – 1157 . ↵ Ott J. ( 2000 ) Predicting the range of linkage disequilibrium. Proc. Natl. Acad. Sci. 97 : 2 – 3 . ↵ Ott J. , Rabinowitz D. ( 1997 ) The effect of marker heterozygosity on the power to detect linkage disequilibrium. Genetics 147 : 927 – 930 . ↵ Pritchard J...
  6. LETTER: Genetic Structure Adds Power to Detect Schizophrenia Susceptibility at SLIT3 in the Chinese Han Population
    • YongYong Shi,
    • XinZhi Zhao,
    • Lan Yu,
    • Ran Tao,
    • JunXia Tang,
    • YuJuan La,
    • Yun Duan,
    • Bo Gao,
    • NiuFan Gu,
    • YiFeng Xu,
    • GuoYin Feng,
    • ShaoMin Zhu,
    • HuiJun Liu,
    • Hugh Salter,
    • and Lin He
    Genome Res. July 2004 14: 1345-1349; doi:10.1101/gr.1758204
    ...the ABI prism panels 1 and 8, where none of the markers have a reported linkage to schizophrenia. These markers were considered to be independent of each other because the minimum space between any two markers is larger than 1.0 cM, beyond the distance at which linkage disequilibrium is important...
  7. METHODS: High-Throughput SNP Allele-Frequency Determination in Pooled DNA Samples by Kinetic PCR
    • Søren Germer,
    • Michael J. Holland,
    • and Russell Higuchi
    Genome Res. February 1, 2000 10: 258-266; doi:10.1101/gr.10.2.258
    ...human diseases. Science 273 : 1516 – 1517 . ↵ Risch N. , Teng J. ( 1998 ) The relative power of family-based and case-control designs for linkage disequilibrium studies of complex diseases I. DNA pooling. Genome Res. 8 : 1273 – 1288 . ↵ Saiki R.K. , Walsh P.S. , Levenson C.H. , Erlich H.A. ( 1988...
  8. LETTER: A Multilocus Genotyping Assay for Candidate Markers of Cardiovascular Disease Risk
    • Suzanne Cheng,
    • Michael A. Grow,
    • Céline Pallaud,
    • William Klitz,
    • Henry A. Erlich,
    • Sophia Visvikis,
    • John J. Chen,
    • Clive R. Pullinger,
    • Mary J. Malloy,
    • Gérard Siest,
    • and John P. Kane
    Genome Res. October 1, 1999 9: 936-949; doi:10.1101/gr.9.10.936
    ...a family-based cohort, and the observed values were consistent with previous reports. Linkage disequilibrium between consecutive pairs of markers within the apoCIII, LPL , and ELAM genes was also estimated. A preliminary analysis of single and pairwise locus associations with severity of atherosclerosis...
  9. Resource: A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines
    • Liming Liang,
    • Nilesh Morar,
    • Anna L. Dixon,
    • G. Mark Lathrop,
    • Goncalo R. Abecasis,
    • Miriam F. Moffatt,
    • and William O.C. Cookson
    Genome Res. April 2013 23: 716-726; Published in Advance January 23, 2013, doi:10.1101/gr.142521.112
    ...components (PCs) of gene expression are highly correlated with RNA extraction and cDNA synthesis dates, the date that the sample was fragmented, and the date of chip hybridization. We go on to show that including these PCs in downstream analyses reduces false positives and increases power for both local...
    OPEN ACCESS ARTICLE
  10. METHODS: Pooled Genotyping of Microsatellite Markers in Parent–Offspring Trios
    • George Kirov,
    • Nigel Williams,
    • Pak Sham,
    • Nick Craddock,
    • and Michael J. Owen
    Genome Res. January 1, 2000 10: 105-115; doi:10.1101/gr.10.1.105
    ...are a powerful alternative for locating genes of small effect in complex traits ( Owen and McGuffin 1993 ; Risch and Merikangas 1996 ). Genome-wide association studies using either case-control or family-based methods are much more sensitive than standard -wide affected-sib-pair linkage analyses ( Risch...
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