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  1. ...by the TORC1 kinase complex, a sensor of nutrient availability. Pol III regulation is thus sensitive to environmental cues, yet a diurnal profile of Pol III transcription activity is so far lacking. Here, we first use gene expression arrays to measure mRNA accumulation during the diurnal cycle in the livers...
  2. ...Human MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest Andrea Orioli 1 , Viviane Praz 1 , 2 , Philippe Lhôte 1 and Nouria Hernandez 1 1Center...
  3. ...version 0.5.9-r16 (Li and Durbin 2009) with default parameters. The genomic locations of tRNA genes were identified by tRNAscan-SE version 1.21 (Lowe and Eddy 1997). Mitochondrial tRNA was excluded from the analysis. Because tRNA genes are frequently duplicated in the (Lowe andEddy1997), reads mapping...
  4. ...of mature mRNAs, such experiments inform on changes occurring at the very first steps of gene expression, i.e., changes in chromatin structure and gene transcription. In such experiments, however, reliable sample normalization has proven difficult. There are a number of different methods to normalize Ch...
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