Searching journal content for articles similar to Reese et al. 13 (10): 2348.

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  1. ...for capturing chromatin histone modification signatures across tissue sections by taking advantage of a double-barcoded DNA arrays design compatible with in situ Protein A–transposase Tn5 tagmentation. This approach has been validated in presence of fresh-frozen mouse brain tissues but also in decalcified...
  2. ...called “fountains,” which have also been reported in zebrafish and mice. These are population average reflections of DNA loops originating from distinct genomic regions and are ∼20–40 kb in C. elegans. Hi-C analysis upon cohesin and WAPL-1 depletion supports the idea that cohesin is preferentially loaded...
  3. ...protocols (Sanvicente-García et al. 2023), in which researchers are interested in discovering the editing patterns. Therefore, the DNA sequence encapsulate a wide array of biological information, varying according to the specific application in focus.k-mers are foundational in bioinformatics, especially...
  4. ..., the pattern with two areas of high density observed in Cast2 and Cast4 is a consequence of the mutual similarity in one part of the sequences between these satDNAs (Supplemental Fig. S3). Despite their partial similarity, they were still considered as individual satDNAs. Considering density plots for all Cast...
  5. ...-Loeffler-Institut, 17493 Greifswald, Germany; 3School of Health Sciences-Biomedical Sciences Program, Missouri State University, Springfield, Missouri 65897, USA A tightly regulated DNA damage response is critical to the overall integrity of the . Here, we combine transcriptomics and proteomics to study DNA damage...
  6. ...contributed equally to this work. Corresponding authors: mi.jain@northeastern.edu,kimberley.billingsley@nih.gov, cornelis.blauwendraat@nih.govAbstractDNA methylation most commonly occurs as 5-methylcytosine (5mC) in the human and has been associated with human diseases. Recent developments in single...
  7. ...of one modality from another. However, existing methods for cross-modality translation between single-cell RNA sequencing (scRNA-seq) and single-cell DNA methylation (scDNAm) data face limitations, including unidirectionality, inadequate modeling of context-specific DNA methylation...
  8. ...with the ribosomal DNA (rDNA) array, which occurs in many copies on the acrocentric Chromosomes 13, 14, 15, 21, and 22 (Agrawal and Ganley 2018; Nurk et al. 2022; Chao et al. 2023). Given this overlap with rDNA, we suspect that the source genes are not protein-coding genes, and manual curation would be required...
  9. ...also been parameterized in the “window protection score” for nucleosome footprinting (Snyder et al. 2016; Straver et al. 2016). Together, these studies highlight that patterns of cfDNA fragmentation are intimately linked to chromatin architecture, such as nucleosome arrays, sites of other DNA...
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