Searching journal content for articles similar to Rajendren et al. 31 (1): 27.

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  1. Research: Dynamic A-to-I RNA editing in response to gut microbiome in honeybees
    • Yuange Duan,
    • Min Huang,
    • Lin Ye,
    • Ling Ma,
    • Yashuai Wu,
    • Yating Du,
    • Jiyao Liu,
    • Fan Song,
    • Li Tian,
    • Wanzhi Cai,
    • Hu Li,
    • Xin Zhou,
    • and Shiqi Luo
    Genome Res. March 4, 2026 ; Published in Advance March 4, 2026, doi:10.1101/gr.280291.124
    ...this gap by comparing the RNA editomes of conventional (CV) and germ-free (GF) honeybees, revealing the complex and dynamic transcriptomic diversity exerted by A-to-I RNA editing, and discover the roles of Adar in the gutmicrobiome-brain axis. Our study indicates that RNA editingmay regulate the honeybee...
  2. Research: Profiling the RNA editomes of wild-type C. elegans and ADAR mutants
    • Han-Qing Zhao,
    • Pan Zhang,
    • Hua Gao,
    • Xiandong He,
    • Yanmei Dou,
    • August Y. Huang,
    • Xi-Ming Liu,
    • Adam Y. Ye,
    • Meng-Qiu Dong,
    • and Liping Wei
    Genome Res. January 2015 25: 66-75; Published in Advance November 4, 2014, doi:10.1101/gr.176107.114
    ...editing in higher eukaryotes. Caenorhabditis elegans has two ADARs, ADR-1 and ADR-2, but their functions remain unclear. Here, we profiled the RNA editomes of C. elegans at different developmental stages of wild-type and ADAR mutants. We developed a new computational pipeline with a ‘‘bisulfite...
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  3. Research: Analyzing super-enhancer temporal dynamics reveals potential critical enhancers and their gene regulatory networks underlying skeletal muscle development
    • Song Zhang,
    • Chao Wang,
    • Shenghua Qin,
    • Choulin Chen,
    • Yongzhou Bao,
    • Yuanyuan Zhang,
    • Lingna Xu,
    • Qingyou Liu,
    • Yunxiang Zhao,
    • Kui Li,
    • Zhonglin Tang,
    • and Yuwen Liu
    Genome Res. December 2024 34: 2190-2202; Published in Advance October 21, 2024, doi:10.1101/gr.278344.123
    ...myofiber formation and hypertrophy stages. By developing an innovative approach integrating SE temporal patterns, eRNA annotation, -wide association study (GWAS) signals, and self-transcribing active regulatory region sequencing (STARR-seq) experiments, Our study not only reveals the critical enhancer...
  4. Research: A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing
    • Konstantin Licht,
    • Utkarsh Kapoor,
    • Fabian Amman,
    • Ernesto Picardi,
    • David Martin,
    • Prajakta Bajad,
    • and Michael F. Jantsch
    Genome Res. September 2019 29: 1453-1463; Published in Advance August 19, 2019, doi:10.1101/gr.242636.118
    ...-to-I editing is regulated during transcript maturation and by mRNA-splicing.ResultsNascent-seq identifies over 90,000 novel editing sitesMost mouse A-to-I editing sites known today locate to exonic regions. To explore the intronic editome, we used Nascent-seq (Menet et al. 2012; Rodriguez et al. 2012...
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  5. Research: A-to-I RNA editing promotes developmental stage–specific gene and lncRNA expression
    • Boaz Goldstein,
    • Lily Agranat-Tamir,
    • Dean Light,
    • Orna Ben-Naim Zgayer,
    • Alla Fishman,
    • and Ayelet T. Lamm
    Genome Res. March 2017 27: 462-470; Published in Advance December 28, 2016, doi:10.1101/gr.211169.116
    .... Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature 387: 303–308. ↵Dallaire A, Proulx S, Simard MJ, Lebel M. 2014. Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span. BMC...
  6. Research: Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes
    • Huiquan Liu,
    • Qinhu Wang,
    • Yi He,
    • Lingfeng Chen,
    • Chaofeng Hao,
    • Cong Jiang,
    • Yang Li,
    • Yafeng Dai,
    • Zhensheng Kang,
    • and Jin-Rong Xu
    Genome Res. April 2016 26: 499-509; Published in Advance March 2, 2016, doi:10.1101/gr.199877.115
    ...Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes Huiquan Liu 1 , Qinhu Wang 1 , Yi He 2 , Lingfeng Chen 1 , Chaofeng Hao 1 , Cong Jiang 1 , Yang Li 3 , Yafeng Dai 1 , Zhensheng Kang 1...
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  7. Resource: A biochemical landscape of A-to-I RNA editing in the human brain transcriptome
    • Masayuki Sakurai,
    • Hiroki Ueda,
    • Takanori Yano,
    • Shunpei Okada,
    • Hideki Terajima,
    • Toutai Mitsuyama,
    • Atsushi Toyoda,
    • Asao Fujiyama,
    • Hitomi Kawabata,
    • and Tsutomu Suzuki
    Genome Res. March 2014 24: 522-534; Published in Advance January 9, 2014, doi:10.1101/gr.162537.113
    .... ICE-seq detected novel editing sites in various repeat elements as well as in short hairpins. Gene ontology analysis revealed that these edited mRNAs are associated with transcription, energy metabolism, and neurological disorders, providing new insights into various aspects of human brain functions...
  8. Research: RNA–DNA sequence differences in Saccharomyces cerevisiae
    • Isabel X. Wang,
    • Christopher Grunseich,
    • Youree G. Chung,
    • Hojoong Kwak,
    • Girish Ramrattan,
    • Zhengwei Zhu,
    • and Vivian G. Cheung
    Genome Res. November 2016 26: 1544-1554; Published in Advance September 16, 2016, doi:10.1101/gr.207878.116
    ...@umich.edu Abstract Alterations of RNA sequences and structures, such as those from editing and alternative splicing, result in two or more RNA transcripts from a DNA template. It was thought that in yeast, RNA editing only occurs in tRNAs. Here, we found that Saccharomyces cerevisiae have all 12 types of RNA...
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  9. Method: Accurate identification of A-to-I RNA editing in human by transcriptome sequencing
    • Jae Hoon Bahn,
    • Jae-Hyung Lee,
    • Gang Li,
    • Christopher Greer,
    • Guangdun Peng,
    • and Xinshu Xiao
    Genome Res. January 2012 22: 142-150; Published in Advance September 29, 2011, doi:10.1101/gr.124107.111
    ...motif that may be functionally relevant to editing. Genes with predicted A-to-I editing were significantly enriched with those known to be involved in cancer, supporting the potential importance of cancer-specific RNA editing. A similar profile of DNA–RNA differences as in U87MG was predicted...
  10. Research: Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation
    • Amanda J. Price,
    • Taeyoung Hwang,
    • Ran Tao,
    • Emily E. Burke,
    • Anandita Rajpurohit,
    • Joo Heon Shin,
    • Thomas M. Hyde,
    • Joel E. Kleinman,
    • Andrew E. Jaffe,
    • and Daniel R. Weinberger
    Genome Res. January 2020 30: 1-11; Published in Advance December 18, 2019, doi:10.1101/gr.250217.119
    ....Assessment of RNA editing and nuclear pore components by fraction across cortical developmentWe next profiled RNA editing across fractions and ages, identifying 3064–5840 editing sites per sample and 25,051 unique sites (Supplemental Fig. S7A–E). Of these unique sites, 75.5% were A-to-I edited sites (appears as A...
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