Searching journal content for articles similar to Rahmanian et al. 29 (11): 1900.

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Research: Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation
- Amanda J. Price,
- Taeyoung Hwang,
- Ran Tao,
- Emily E. Burke,
- Anandita Rajpurohit,
- Joo Heon Shin,
- Thomas M. Hyde,
- Joel E. Kleinman,
- Andrew E. Jaffe,
- and Daniel R. Weinberger
Genome Res. January 2020 30: 1-11; Published in Advance December 18, 2019, doi:10.1101/gr.250217.119
...homogenate prenatal and adult human postmortem cortex using poly(A)+ and Ribo-Zero library preparation methods. We find that while many genes are differentially expressed by fraction and developmental expression changes are similarly detectable in nuclear and cytoplasmic RNA, the compartmented transcriptomes...
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Research: Single-cell multi-omics of human preimplantation embryos shows susceptibility to glucocorticoids
- Cheng Zhao,
- Savana Biondic,
- Katherine Vandal,
- Åsa K. Björklund,
- Michael Hagemann-Jensen,
- Theresa Maria Sommer,
- Jesica Canizo,
- Stephen Clark,
- Pascal Raymond,
- Daniel R. Zenklusen,
- Nicolas Rivron,
- Wolf Reik,
- and Sophie Petropoulos
Genome Res. September 2022 32: 1627-1641; Published in Advance August 10, 2022, doi:10.1101/gr.276665.122
...of extravillous trophoblast markers in the polar sublineage and presence of X Chromosome dosage compensation. Further, we have elucidated that epigenetic regulation—DNA methylation and microRNAs (miRNAs)—likely underlies the transcriptional changes observed. This study suggests that exposures to exogenous...
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Perspective: Short arms of human acrocentric chromosomes and the completion of the human genome sequence
- Stylianos E. Antonarakis
Genome Res. April 2022 32: 599-607; Published in Advance March 31, 2022, doi:10.1101/gr.275350.121
...accurate mapping will await the results of the T2T Project (Miga et al. 2020; Logsdon et al. 2021; https://sites.google.com/ucsc.edu/t2tworkinggroup). These include members of the BAGE family of genes (Boël et al. 1995), tektin pseudogenes, long intergenic non-protein-coding RNA 1667 (LINC01667), microRNA...
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Research: Tracing human stem cell lineage during development using DNA methylation
- Lucas A. Salas,
- John K. Wiencke,
- Devin C. Koestler,
- Ze Zhang,
- Brock C. Christensen,
- and Karl T. Kelsey
Genome Res. September 2018 28: 1285-1295; Published in Advance August 2, 2018, doi:10.1101/gr.233213.117
...candidates with regulatory function in stem cell maturation. A notable example is our finding of DMRs in the Chromosome 22 region containing a cluster of let-7 microRNAs. Extensive research has shown that expression of let-7 microRNAs play essential roles in the differentiation of ESCs (Lee et al. 2016...
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Research: Pervasive polymorphic imprinted methylation in the human placenta
- Courtney W. Hanna,
- Maria S. Peñaherrera,
- Heba Saadeh,
- Simon Andrews,
- Deborah E. McFadden,
- Gavin Kelsey,
- and Wendy P. Robinson
Genome Res. June 2016 26: 756-767; Published in Advance January 14, 2016, doi:10.1101/gr.196139.115
...) and the Chromosome 19 microRNA cluster (C19MC) (Noguer-Dance et al. 2010). There are also examples of loci where biallelic expression has been documented despite a nearby imprinted DMR, such as at RASGRF1 and C3orf62 (Yuen et al. 2011a). This suggests that additional factors may be important for imprinted gene...
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Research: Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation
- Clara Y. Cheong,
- Keefe Chng,
- Shilen Ng,
- Siew Boom Chew,
- Louiza Chan,
- and Anne C. Ferguson-Smith
Genome Res. May 2015 25: 611-623; Published in Advance April 10, 2015, doi:10.1101/gr.183301.114
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Perspective: Transgenerational epigenetic inheritance: More questions than answers
- Lucia Daxinger and
- Emma Whitelaw
Genome Res. December 2010 20: 1623-1628; Published in Advance November 1, 2010, doi:10.1101/gr.106138.110
...-type males. Paramutation could be induced following microinjection of microRNAs targeted to the Kit locus (Rassoulzadegan et al. 2006). However, concerns have been raised regarding the particular phenotype. The white tail is found surprisingly frequently in inbred C57BL/6 mice obtained from the Jackson Lab...
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Research: Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques
- Xiling Liu,
- Mehmet Somel,
- Lin Tang,
- Zheng Yan,
- Xi Jiang,
- Song Guo,
- Yuan Yuan,
- Liu He,
- Anna Oleksiak,
- Yan Zhang,
- Na Li,
- Yuhui Hu,
- Wei Chen,
- Zilong Qiu,
- Svante Pääbo,
- and Philipp Khaitovich
Genome Res. April 2012 22: 611-622; Published in Advance February 2, 2012, doi:10.1101/gr.127324.111
...into the prenatal stage by measuring PFC expression in six fetal samples at ;70 to ;30 d before birth and in six newborn macaque samples with ages between 0.5 d and 3 yr (Supplemental Table S1). This revealed that both module 1 and module 3 genes follow the same developmental trajectories in humans andmacaques...
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Resource: PRISM offers a comprehensive genomic approach to transcription factor function prediction
- Aaron M. Wenger,
- Shoa L. Clarke,
- Harendra Guturu,
- Jenny Chen,
- Bruce T. Schaar,
- Cory Y. McLean,
- and Gill Bejerano
Genome Res. May 2013 23: 889-904; Published in Advance February 4, 2013, doi:10.1101/gr.139071.112
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