Searching journal content for articles similar to Ragle et al. 25 (7): 982.

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  1. ...24 and Rbm38), which have both been implicated in alternative splicing regulation in C. elegans (Kuroyanagi et al. 2007). We also identified enriched cis elements recognized by UNC-75/CELF and EXC-7 (an ortholog of Elavl4/HuD), both known to regulate tissue-specific alternative splicing within...
  2. ...of trimethylation of histone H3 lysine 4 are prone to changes during aging in Caenorhabditis elegans somatic cells. PLoS Genet 14: e1007466. doi:10.1371/journal.pgen.1007466 ↵Ragle JM, Katzman S, Akers TF, Barberan-Soler S, Zahler AM. 2015. Coordinated tissue-specific regulation of adjacent alternative 3′ splice...
  3. ...Foundation for Statistical Computing, Vienna, Austria. http://www.R-project.org/. ↵Ragle JM, Katzman S, Akers TF, Barberan-Soler S, Zahler AM. 2015. Coordinated tissue-specific regulation of adjacent alternative 3′ splice sites in C. elegans. Genome Res 25: 982–994. ↵Ramani AK, Nelson AC, Kapranov P, Bell I...
  4. ...These authors contributed equally to this work. Corresponding author: zyzhao@hkbu.edu.hkAbstractMassively parallel sequencing of the polyadenylated RNAs has played a key role in delineating transcriptome complexity, including alternative use of an exon, promoter, 5′ or 3′ splice site or polyadenylation site...
  5. ...hypothesis testing correction (Supplemental Table 4). This is possibly due to lack of coverage but more likely reflects an overall lack of coordination between splicing and polyadenylation site choice in C. elegans.Quantifying genes and splice isoforms captured with full-length supportLess than half...
  6. ...Transcription factor redundancy and tissue-specific regulation: Evidence from functional and physical network connectivity Steven G. Kuntz 1 , Brian A. Williams 1 , Paul W. Sternberg 1 , 2 , 3 and Barbara J. Wold 1 , 3 1 Division...
  7. ...(RBPs) can bind, substantially impacting gene expression (Matlin et al. 2005; Bartel 2009). Although its function in eukaryotes is still not fully understood, a recent study revealed that APA may occur in a tissue-specific manner and, at least in the nematode Caenorhabditis elegans, is used in specific...
  8. ...-1 family and SUP-12 coordinately regulate tissue-specific alternative splicing in vivo. Mol Cell Biol 27: 8612–8621. Licatalosi DD, Darnell RB. 2010. RNA processing and its regulation: global insights into biological networks. Nat Rev Genet 11: 75–87. Lopez AJ. 1998. Alternative splicing of pre...
  9. ...and previously annotated micro-exons across all 901 RNA-seq samples (Methods).Micro-exons possess tissue-specific inclusion patternsWe quantified the splicing inclusion ratios of micro-exons across all RNA-seq samples assigning PSI (percent spliced-in) values for each micro-exon and sample. Given our initial...
  10. ...of other types of AS events. Usage of A5SS and A3SS is themost prominent in liver, and ES events are themost frequent in brain and testis; this was attributed to tissue-specific combinations and levels of splicing factors regulating particular events (Yeo et al. 2004). It has been suggested that the high...
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