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  1. ...occur within 2.5 kb of the transcription start sites. We have shown that changes in histone acetylation alone do not necessarily correlate with differential gene expression. Our findings are different from observations which have typically focused on a subset of genes (Suzuki et al. 2002). While our...
  2. ...activators and repressors, respectively, as well as their roles in cancer pathology renders the H3.3-NuRD interaction of particular importance to the modulation of gene transcription. NuRD activity is generally thought of as a factor mediating gene repression through histone deacetylation. Nevertheless -wide...
  3. ...in transport and metabolism of lipids and other nutrients were generally down-regulated by microbiota in both the ileum and colon. Together, our RNA-seq data revealed that gut microbiota elicit -wide alterations to host gene transcription in the intestinal epithelium, a response that varies depending...
  4. ...incidence (Egi et al. 2016). Conversely, in N. vitripennis, down-regulation of DNA methyltransferases enhanced diapause (Pegoraro et al. 2016). Additionally, the expression of multiple genes regulating histone methylation and acetylation changed with diapause (Reynolds et al. 2013, 2016). In Helicoverpa...
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