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  1. ...crucial genes and pathways are underpinning the fitness advantages of cancer cells. Such mutations may be found by recurrence analysis across patients and even across cancer types, at least in the coding fraction of the (Bailey et al. 2018). In the noncoding , however, this approach typically breaks down...
  2. ...′ UTR secondary structure to enhance translational efficiency Stable secondary structures in the 5′ terminus of an mRNA can slow down ribosome scanning or translocation at the initiation step and thus reduce translational efficiency (Sen et al. 2015). Therefore, we hypothesized that SL1 transsplicing...
  3. ...–24 nucleotides (nt) long (Lee et al. 1993; Wightman et al. 1993; Lagos-Quintana et al. 2001; Lau et al. 2001; Lee and Ambros 2001). They normally guide the so-called RNA-induced silencing protein (RISC) complex to down-regulate transcripts that contain miR-matching sequences in their 39 UTRs. The rules...
  4. ...that DICER1 and EHMT2 contribute to shaping the chromatin landscape surrounding the proximal CPA site in ETNK1, forcing RNA polymerase to slow down, which in turn may favor proximal PAS recognition. How far reaching this process is remains to be explored. Discussion Our comparison between cytoplasmic...
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