Searching journal content for articles similar to Ponts et al. 20 (2): 228.

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  1. Research: Transcriptional variation in the malaria parasite Plasmodium falciparum
    • Núria Rovira-Graells,
    • Archna P. Gupta,
    • Evarist Planet,
    • Valerie M. Crowley,
    • Sachel Mok,
    • Lluís Ribas de Pouplana,
    • Peter R. Preiser,
    • Zbynek Bozdech,
    • and Alfred Cortés
    Genome Res. May 2012 22: 925-938; Published in Advance March 13, 2012, doi:10.1101/gr.129692.111
    ...genetic variation has been extensively characterized, but the level of epigenetic plasticity remains largely unexplored. Here we provide a comprehensive characterization of transcriptional variation in the most lethal malaria parasite, Plasmodium falciparum, based on highly accurate transcriptional...
  2. Research: DNA-guided establishment of nucleosome patterns within coding regions of a eukaryotic genome
    • Leslie Y. Beh,
    • Manuel M. Müller,
    • Tom W. Muir,
    • Noam Kaplan,
    • and Laura F. Landweber
    Genome Res. November 2015 25: 1727-1738; Published in Advance September 1, 2015, doi:10.1101/gr.188516.114
    ...array of well-positioned nucleosomes downstream from transcription start sites (TSS). Recent studies indicate that trans-acting factors establish this stereotypical array. Here, we present the first -wide in vitro and in vivo nucleosomemaps for the ciliate Tetrahymena thermophila. In contrast...
  3. Research: High nucleosome occupancy is encoded at X-linked gene promoters in C. elegans
    • Sevinç Ercan,
    • Yaniv Lubling,
    • Eran Segal,
    • and Jason D. Lieb
    Genome Res. February 2011 21: 237-244; Published in Advance December 22, 2010, doi:10.1101/gr.115931.110
    ...G, Lonardi S, Le Roch KG. 2010. Nucleosome landscape and control of transcription in the human malaria parasite. Genome Res 20: 228–238. Prunell A, Kornberg RD. 1982. Variable center to center distance of nucleosomes in chromatin. J Mol Biol 154: 515–523. Rechtsteiner A, Ercan S, Takasaki T, Phippen...
  4. Research: Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression
    • Ferhat Ay,
    • Evelien M. Bunnik,
    • Nelle Varoquaux,
    • Sebastiaan M. Bol,
    • Jacques Prudhomme,
    • Jean-Philippe Vert,
    • William Stafford Noble,
    • and Karine G. Le Roch
    Genome Res. June 2014 24: 974-988; Published in Advance March 26, 2014, doi:10.1101/gr.169417.113
    ...repressive centers, as well as the differential localization of the single active var gene. In conclusion, this study demonstrates the unique role of organization in transcriptional regulation in the human malaria parasite. In other eukaryotes such as human and mouse, organization has been shown...
  5. Research: Copy number variation alters local and global mutational tolerance
    • Grace Avecilla,
    • Pieter Spealman,
    • Julia Matthews,
    • Elodie Caudal,
    • Joseph Schacherer,
    • and David Gresham
    Genome Res. August 2023 33: 1340-1353; Published in Advance August 31, 2023, doi:10.1101/gr.277625.122
    ...in novel genetic interactions with unlinked genes. We validated a novel genetic interaction between different CNVs and BMH1 that was common to multiple strains. We also analyzed global gene expression and found that transcriptional dosage compensation does not affect most genes amplified by CNVs, although...
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