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Pizzi and Frontali 11 (2): 218
.
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26
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:
Indels, structural variation, and recombination drive genomic diversity in
Plasmodium falciparum
Alistair Miles
,
Zamin Iqbal
,
Paul Vauterin
,
Richard Pearson
,
Susana Campino
,
Michel Theron
,
Kelda Gould
,
Daniel Mead
,
Eleanor Drury
,
John O'Brien
,
Valentin Ruano Rubio
,
Bronwyn MacInnis
,
Jonathan Mwangi
,
Upeka Samarakoon
,
Lisa Ranford-Cartwright
,
Michael Ferdig
,
Karen Hayton
,
Xin-zhuan Su
,
Thomas Wellems
,
Julian Rayner
,
Gil McVean
,
and
Dominic Kwiatkowski
Genome Res.
September 2016
26
:
1288
-
1299
;
Published in Advance
August 16, 2016
,
doi:
10.1101/gr.203711.115
...Indels, structural variation, and recombination drive genomic diversity in
Plasmodium
falciparum
Alistair Miles 1 , 2 , Zamin Iqbal 3 , Paul Vauterin 1 , Richard Pearson 1 , 2 , Susana Campino 2 , Michel Theron 2 , Kelda...
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INSIGHT/OUTLOOK
:
Low-Complexity Regions in
Plasmodium
Proteins: In Search of a Function
Luciano Brocchieri
Genome Res.
February 1, 2001
11
:
195
-
197
;
doi:
10.1101/gr.176401
...In a new window Figure 1. Partial alignment of the ookinete adhesive
protein
between the
Plasmodium
falciparum
(PLAFA) and the rodent malaria agent
Plasmodium
berghei (PLABE) sequences, showing two
low-complexity
elements (lower case, unaligned) between
regions
of alignment (upper case). The first
region
...
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Resource
:
Long-read assembly and comparative evidence-based reanalysis of
Cryptosporidium
genome sequences reveal expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions
Rodrigo P. Baptista
,
Yiran Li
,
Adam Sateriale
,
Mandy J. Sanders
,
Karen L. Brooks
,
Alan Tracey
,
Brendan R.E. Ansell
,
Aaron R. Jex
,
Garrett W. Cooper
,
Ethan D. Smith
,
Rui Xiao
,
Jennifer E. Dumaine
,
Peter Georgeson
,
Bernard J. Pope
,
Matthew Berriman
,
Boris Striepen
,
James A. Cotton
,
and
Jessica C. Kissinger
Genome Res.
January 2022
32
:
203
-
213
;
Published in Advance
November 11, 2021
,
doi:
10.1101/gr.275325.121
...to the equivalent 18S/28S rRNA Chr 1 pileups.
Regions
with pileups on inner portions of Chr 5, 7, and 8 are
low
complexity
regions
composed by tandem repeats (Supplemental Table S8). In Chr 5, we have one uncharacterized
protein
(CPATCC_0023030), full of tandem repeats and good RNA-seq support for its expression...
Abstract
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LETTER
:
Genome-wide discovery and verification of novel structured RNAs in
Plasmodium falciparum
Tobias Mourier
,
Celine Carret
,
Sue Kyes
,
Zoe Christodoulou
,
Paul P. Gardner
,
Daniel C. Jeffares
,
Robert Pinches
,
Bart Barrell
,
Matt Berriman
,
Sam Griffiths-Jones
,
Alasdair Ivens
,
Chris Newbold
,
and
Arnab Pain
Genome Res.
February 2008
18
:
281
-
292
;
Published in Advance
December 20, 2007
,
doi:
10.1101/gr.6836108
...% of the . These sequences were searched for similarity against the other
Plasmodium
s using WU-BLASTN ( http://blast.wustl.edu/ ) with dust and seg
low-complexity
filters. Only hits with a length ≥50 bp and with at least 70% identity were further processed. BLAST-matches were mapped back at the P.
falciparum
and merged...
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LETTER
:
Systematic genome-wide annotation of spliceosomal proteins reveals differential gene family expansion
Nuno L. Barbosa-Morais
,
Maria Carmo-Fonseca
,
and
Samuel Aparício
Genome Res.
January 2006
16
:
66
-
77
;
Published in Advance
December 12, 2005
,
doi:
10.1101/gr.3936206
...(Mmus), chicken (Ggal), Fugu (Frub), Ciona (Cint), fruit fly (Dmel), C. elegans (Cele), Arabidopsis (Atha), and
Plasmodium
(Pfal) (for simplicity only one rodent, one teleost, and one insect are shown). Amino-acid positions of each domain within the
protein
are also indicated in the domain...
Abstract
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LETTER
:
Functional insights from the distribution and role of homopeptide repeat-containing proteins
Noel G. Faux
,
Stephen P. Bottomley
,
Arthur M. Lesk
,
James A. Irving
,
John R. Morrison
,
Maria Garcia de la Banda
,
and
James C. Whisstock
Genome Res.
April 2005
15
:
537
-
551
;
doi:
10.1101/gr.3096505
...highlight several interesting anomalies. Drosophila melanogaster possesses an overabundance of poly-Q RCPs, >3.5-fold more than that of Homo sapiens and sixfold more than another insect, the mosquito Anopheles gambiae ( Fig. 3B ). In contrast, poly-Q repeats are extremely rare in
Plasmodium
falciparum
...
Abstract
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Method
:
Detection of simple and complex de novo mutations with multiple reference sequences
Kiran V. Garimella
,
Zamin Iqbal
,
Michael A. Krause
,
Susana Campino
,
Mihir Kekre
,
Eleanor Drury
,
Dominic Kwiatkowski
,
Juliana M. Sá
,
Thomas E. Wellems
,
and
Gil McVean
Genome Res.
August 2020
30
:
1154
-
1169
;
Published in Advance
August 19, 2020
,
doi:
10.1101/gr.255505.119
...and evaluate the approach using extensive simulations and use it to characterize the rate and spectrum of de novo mutation events in 119 progeny from four
Plasmodium
falciparum
experimental crosses, using long-read data on the parents to inform reconstructions of the progeny and to detect several known...
Abstract
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Research
:
Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals
Ulrike Böhme
,
Thomas D. Otto
,
James A. Cotton
,
Sascha Steinbiss
,
Mandy Sanders
,
Samuel O. Oyola
,
Antoine Nicot
,
Sylvain Gandon
,
Kailash P. Patra
,
Colin Herd
,
Ellen Bushell
,
Katarzyna K. Modrzynska
,
Oliver Billker
,
Joseph M. Vinetz
,
Ana Rivero
,
Chris I. Newbold
,
and
Matthew Berriman
Genome Res.
April 2018
28
:
547
-
560
;
Published in Advance
March 2, 2018
,
doi:
10.1101/gr.218123.116
...1 and SURFIN families, respectively. Next, we searched for those predicted motifs in all predicted
proteins
(excluding
low-complexity
regions
) of the 11 sequenced
Plasmodium
species and visualized the results as a binary occurrence matrix (Supplemental Fig. S14B). Although some
proteins
share...
Abstract
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Method
:
Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants
Iraad F. Bronner
,
Thomas D. Otto
,
Min Zhang
,
Kenneth Udenze
,
Chengqi Wang
,
Michael A. Quail
,
Rays H.Y. Jiang
,
John H. Adams
,
and
Julian C. Rayner
Genome Res.
July 2016
26
:
980
-
989
;
Published in Advance
May 10, 2016
,
doi:
10.1101/gr.200279.115
...Bac mutants in the human malaria parasite
Plasmodium
falciparum
but should be applicable to many other eukaryotic genomes. QIseq proved accurate, confirming known sites in >100 mutants, and sensitive, identifying and monitoring sites over a >10,000-fold dynamic range of sequence counts. Applying QIseq...
Abstract
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Letter
:
Nucleosome landscape and control of transcription in the human malaria parasite
Nadia Ponts
,
Elena Y. Harris
,
Jacques Prudhomme
,
Ivan Wick
,
Colleen Eckhardt-Ludka
,
Glenn R. Hicks
,
Gary Hardiman
,
Stefano Lonardi
,
and
Karine G. Le Roch
Genome Res.
February 2010
20
:
228
-
238
;
Published in Advance
January 6, 2010
,
doi:
10.1101/gr.101063.109
.....org Nucleosome positioning in
Plasmodium
protein
-free DNA than histone-bound
regions
and can be accessed by any type of DNA-binding
proteins
during most of the erythrocytic cycle, especially at the trophozoite and early schizont stages (18–30 hpi). We verified that this abundance of
protein
-free
regions
...
Abstract
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