Searching journal content for articles similar to Picart-Picolo et al. 30 (11): 1583.

Displaying results 1-10 of 50
For checked items
  1. ...These authors contributed equally to this review. Corresponding author: christopher.pearson@sickkids.caAbstractExpansions of gene-specific DNA tandem repeats (TRs), first described in 1991 as a disease-causing mutation in humans, are now known to cause >60 phenotypes, not just disease, and not only in humans...
  2. ...in some plant lineages (Clark et al. 2007; Xu et al. 2009).The abundance of STRs in eukaryotic promoters (Sawaya et al. 2013), and their associations with gene expression (in cis) (Vinces et al. 2009; Bilgin Sonay et al. 2015; Gymrek et al. 2015), suggested that STRs affect transcription, possibly...
  3. ...(ChenandNi 2006;Gaeta et al. 2006; Tate et al. 2009; Wang et al. 2010). Clusters of duplicated genes have also formed through tandem duplication (TD) processes, which have greatly expanded some gene families, such as the Nucleotide Binding Site-Leucine Rich Repeat (NBS-LRR) subset of plant resistance genes...
  4. ...results suggest that asexual pathogens may evolve by prompting chromosomal rearrangements, enabling rapid development of novel effector genes. Likely, chromosomal reshuffling can act as a general mechanism for adaptation in asexually propagating organisms. [Supplemental material is available...
  5. ...segments, which promote reduction and expansion of the gene repertoire, respectively (Llorente et al. 2000; Dujon et al. 2004; Wapinski et al. 2007; Butler et al. 2009; Souciet et al. 2009; Scannell et al. 2011;Gabaldonet al. 2013).Whole-duplication (WGD) and hybridization events also affect gene...
  6. ..., demonstrating an unprecedented putative cis-regulatory role of Helitrons in Drosophila. Differential expression analysis between species with different preferred hosts reveals divergence in gene expression in heads and larvae. Although TEs’ presence does not affect overall gene expression, we observe 6...
  7. ...were KIAA1549–BRAF exon 16–exon 11 (PA27) and SRGAP3–RAF1 exon 11–exon 8 (PA30). Our initial characterization of the SRGAP3– RAF1 fusion identified an internal tandem duplication of SRGAP3 exon 11, which enables the resultant fusion gene to be in-frame (Forshew et al. 2009). We successfully sequenced...
  8. ...(Fig. 2A). Alignment of the protein products using BLASTP indicates that the first three members have ;60% identity and 70% positive amino acids, with a fourth more divergent member (MEG-3.4; ;25% identity and 40%positive).We interpret this organization to be the result of a series of gene duplications...
  9. ...boundary duplications largely overlap with functional regulatory elements and genes argues for further examining the forces shaping enrichment of TDs at TAD boundaries. Collectively, our findings offer novel insight into the evolutionary significance of spatial organization in shaping patterns of large...
  10. ...manifested by rapid tandem duplications, a high proportion of pseudogenes, and a rapid diversification of LRR regions relative to the conservation of TIR domains ( Hibino et al. 2006 ). As for the V-TLRs outside the SC75 lineage, judging from the branching pattern and degree of TIR sequence divergence...
For checked items

Preprint Server