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Petti and Church 15 (9): 1298
.
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36
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Research
:
Cohesin regulates tissue-specific expression by stabilizing highly occupied
cis
-regulatory modules
Andre J. Faure
,
Dominic Schmidt
,
Stephen Watt
,
Petra C. Schwalie
,
Michael D. Wilson
,
Huiling Xu
,
Robert G. Ramsay
,
Duncan T. Odom
,
and
Paul Flicek
Genome Res.
November 2012
22
:
2163
-
2175
;
Published in Advance
July 10, 2012
,
doi:
10.1101/gr.136507.111
...Cohesin regulates tissue-specific expression by stabilizing highly occupied cis -regulatory
modules
Andre J. Faure 1 , 7 , Dominic Schmidt 2 , 3 , 7 , Stephen Watt 2 , 3 , Petra C. Schwalie 1 , Michael D. Wilson 2 , 3 , 8...
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:
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation
Hélène Neyret-Kahn
,
Moussa Benhamed
,
Tao Ye
,
Stéphanie Le Gras
,
Jack-Christophe Cossec
,
Pierre Lapaquette
,
Oliver Bischof
,
Maia Ouspenskaia
,
Mary Dasso
,
Jacob Seeler
,
Irwin Davidson
,
and
Anne Dejean
Genome Res.
October 2013
23
:
1563
-
1579
;
Published in Advance
July 26, 2013
,
doi:
10.1101/gr.154872.113
...Sumoylation at chromatin governs
coordinated
repression of a transcriptional program essential for cell growth and proliferation Hélène Neyret-Kahn 1 , 2 , 3 , Moussa Benhamed 1 , 2 , 3 , 6 , Tao Ye 4 , Stéphanie Le Gras 4 , Jack...
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LETTER
:
Control of Yeast Filamentous-Form Growth by Modules in an Integrated Molecular Network
Susanne Prinz
,
Iliana Avila-Campillo
,
Christine Aldridge
,
Ajitha Srinivasan
,
Krassen Dimitrov
,
Andrew F. Siegel
,
and
Timothy Galitski
Genome Res.
March 2004
14
:
380
-
390
;
doi:
10.1101/gr.2020604
...of the clusters to
modules
is supported by significant
coordinated
expression change among cluster co-member genes, and the quantitative identification of collective functions controlling cell properties. The modular abstraction of the filamentation
network
enables the association of filamentous-form cell...
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Article
:
A canonical promoter organization of the transcription machinery and its regulators in the
Saccharomyces
genome
Bryan J. Venters
and
B. Franklin Pugh
Genome Res.
March 2009
19
:
360
-
371
;
Published in Advance
January 5, 2009
,
doi:
10.1101/gr.084970.108
...representative components of the gene regulatory machinery in
Saccharomyces
cerevisiae
to an experimental resolution of <40 bp. Sequence-specific gene regulators, chromatin regulators, mediator, and RNA polymerase (Pol) II were found primarily near the downstream border from the “−1” nucleosome, which abuts...
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Method
:
System-wide analyses of the fission yeast poly(A)
+
RNA interactome reveal insights into organization and function of RNA–protein complexes
Cornelia Kilchert
,
Tea Kecman
,
Emily Priest
,
Svenja Hester
,
Ebru Aydin
,
Krzysztof Kus
,
Oliver Rossbach
,
Alfredo Castello
,
Shabaz Mohammed
,
and
Lidia Vasiljeva
Genome Res.
July 2020
30
:
1012
-
1026
;
Published in Advance
June 18, 2020
,
doi:
10.1101/gr.257006.119
...). For reference, standard gene names for enriched RPs are given in Supplemental Fig. S2B. (B) Structure of the
Saccharomyces
cerevisiae
80S ribosome [PDB:5MC6] (Schmidt et al. 2016). RPs with S. pombe orthologs that were highly significantly enriched on poly(A)+ RNA are designated in blue. For reference, the m...
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:
DDX54 regulates transcriptome dynamics during DNA damage response
Miha Milek
,
Koshi Imami
,
Neelanjan Mukherjee
,
Francesca De Bortoli
,
Ulrike Zinnall
,
Orsalia Hazapis
,
Christian Trahan
,
Marlene Oeffinger
,
Florian Heyd
,
Uwe Ohler
,
Matthias Selbach
,
and
Markus Landthaler
Genome Res.
August 2017
27
:
1344
-
1359
;
Published in Advance
June 8, 2017
,
doi:
10.1101/gr.218438.116
...by a well-characterized
network
of DNA surveillance pathways. The contribution of post-transcriptional gene regulatory
networks
to the DNAdamage response (DDR) has not been extensively studied. Here, we systematically identified RNA-binding proteins differentially interacting with polyadenylated transcripts...
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Research
:
Chromatin signatures of the
Drosophila
replication program
Matthew L. Eaton
,
Joseph A. Prinz
,
Heather K. MacAlpine
,
George Tretyakov
,
Peter V. Kharchenko
,
and
David M. MacAlpine
Genome Res.
February 2011
21
:
164
-
174
;
Published in Advance
December 22, 2010
,
doi:
10.1101/gr.116038.110
...DNA replication initiates from thousands of start sites throughout the Drosophila genome and must be
coordinated
with other ongoing nuclear processes such as transcription to ensure genetic and epigenetic inheritance. Considerable progress has been made toward understanding how chromatin...
Abstract
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Research
:
Synergistic regulation by H3K36 and H3K27 methylation defines the chromatin landscape to control virulence and secondary metabolism in a fungal pathogen
Xingmin Han
,
Chenghui Xu
,
Yiyi Ren
,
Meiling Guo
,
Jiayue Yan
,
Xuan Wang
,
Chao Liu
,
Qin Gu
,
Xing-Xing Shen
,
Zhonghua Ma
,
and
Yun Chen
Genome Res.
November 2025
35
:
2472
-
2487
;
Published in Advance
October 14, 2025
,
doi:
10.1101/gr.280560.125
...additional functions of Set2. Loss of SET2 in
Saccharomyces
cerevisiae
leads to increased histone exchange and H3K56ac accumulation within gene bodies, facilitating aberrant transcriptional activation (Venkatesh et al. 2012). Set2-mediated H3K36 methylation is critical for proper pre-mRNA splicing, and its...
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Research
:
Tyrosine 1–phosphorylated RNA polymerase II transcribes PROMPTs to facilitate proximal promoter pausing and induce global transcriptional repression in response to DNA damage
Kamal Ajit
,
Adele Alagia
,
Kaspar Burger
,
and
Monika Gullerova
Genome Res.
February 2024
34
:
201
-
216
;
Published in Advance
March 11, 2024
,
doi:
10.1101/gr.278644.123
...phosphorylates Y1 in the CTD of RNA Pol II. Up-regulation of ABL1 was also reported as a consequence of activation of upstream DDR regulators such as DNA-dependent protein kinase (DNA-PK) and ATM. Another study (Yurko et al. 2017) showed overall increased levels of Y1P following IR in
Saccharomyces
cerevisiae
...
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Research
:
Sir3 mediates long-range chromosome interactions in budding yeast
Myriam Ruault
,
Vittore F. Scolari
,
Luciana Lazar-Stefanita
,
Antoine Hocher
,
Isabelle Loïodice
,
Romain Koszul
,
and
Angela Taddei
Genome Res.
March 2021
31
:
411
-
425
;
Published in Advance
February 12, 2021
,
doi:
10.1101/gr.267872.120
...of
Saccharomyces
cerevisiae
cluster within 3 to 5 foci mainly found at the nuclear periphery, where the silencing information regulators Sir2, Sir3, and Sir4, forming the SIR complex, concentrate (Gotta et al. 1996). These clusters represent a well-documented example of a repressive nuclear subcompartment (Kueng...
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