Searching journal content for articles similar to Peterson et al. 9 (9): 844.

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  1. ...variants into causal and noncausal, referring to variants neither truly associated with the phenotype nor in linkage disequilibrium (LD) with causal variants. We assumed that any systematic differences in calculated P-values or effect sizes of noncausal variants in between the two models are likely owing...
  2. ...Francisco, San Francisco, California 94158, USA; 3Chan-Zuckerberg Biohub, San Francisco, California 94158, USA Corresponding author: kpollard@gladstone.ucsf.eduAbstractChromatin interactions and linkage disequilibrium (LD) are both pairwise measurements between genomic loci that show block patterns along...
  3. ...). However, because MGEs are vehicles for the exchange of beneficial accessory genes, defense systems could consequently impede rapid adaptation in microbial populations. Here, we study how defense systems impact horizontal gene transfer (HGT) in the short term and long term. By combining comparative...
  4. ...samples with a mean per site depth of 14.75× and mean frequency of missingness of 0.11 (Supplemental Table S2). For analyses dependent on allele frequencies, such as principal component analysis (PCA)-based analyses, we pruned SNPs based on linkage disequilibrium (LD), resulting in a data set of 19...
  5. ...was performed using the pairwise allele-sharing genetic distance. Following vonHoldt et al. (2011), sites exhibiting apparent strong local linkage disequilibrium (R2 > 0.5) were filtered using the –indep option in PLINK (–indep 50 5 0.2) (Purcell et al. 2007). To improve resolution among wolves, the two golden...
  6. ...is a painfully crowded and complex environment for proteins to find and associate with each other faithfully in a timely and well-organized manner, as required by signal transduction, especially if the population and distribution of individual proteins were entirely random or independent...
  7. ....Within-population genetic indicesTo gain further insight into the genetic differentiation of the two populations in the “Western” lineage (i.e., populations 2 and 3), we calculated linkage disequilibrium (LD) decay, Tajima's D values, and nucleotide diversity (π).We found that population 3 had a slower...
  8. ...for standard MR methods (Supplemental Fig. S2). We observed inflated FPR for standard MR methods even when there is no confounding (stratification) for large values of FST (Supplemental Fig. S2) likely owing to correlation or linkage disequilibrium (LD) among the genetic variants induced by population...
  9. ...Human population dispersal “Out of Africa” estimated from linkage disequilibrium and allele frequencies of SNPs Brian P. McEvoy 1 , 4 , Joseph E. Powell 1 , 4 , 5 , Michael E. Goddard 2 , 3 and Peter M. Visscher 1 1Queensland...
  10. ...Recent human effective population size estimated from linkage disequilibrium Albert Tenesa 1 , 2 , 3 , Pau Navarro 3 , Ben J. Hayes 4 , David L. Duffy 5 , Geraldine M. Clarke 6 , Mike E. Goddard 4 , 7 , and Peter M...
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