Searching journal content for articles similar to Peterson et al. 9 (12): 1250.

Displaying results 1-10 of 311
For checked items
  1. ...chromosome, one end of which is nonhomologous and thus nonrecombining, and Chromosomes 8 and 9 (as determined by cytogenetics) (Divashuk et al. 2014), which harbor 5S rDNA and 45S rDNA on one arm, respectively. The repetitive nature of these regions would be expected to impede both assembly and mapping...
  2. ...-C contact maps have been published from species of Amoebozoa. Although a Hi-C library was generated on Entamoeba histolytica for the purpose of scaffolding (Kawano-Sugaya et al. 2020), its quality was too poor to yield a contact map of good quality. Here, the Hi-C reads we used to generate the chromosome...
  3. ...of targeted BAC clone sequence) to the pig, human, and mouse assemblies. A comprehensive analysis of annotated X-linked orthologs in public databases demonstrated that the majority of ampliconic gene families were present on the ancestral placental X Chromosome. We generated a domestic cat Hi-C contact map...
  4. ...to the chromatin polymeric backbone. This co-alignment of chromosome arms is also visible in the cumulated inter-chromosome contact maps of the 100-kb subtelomeric regions and is very similar to the one observed in pericentromeric regions in G2/M phase (Supplemental Fig. S1B; Schalbetter et al. 2017). In wild...
  5. .... Multiplexed integrated accessibility assay (MIAA) measures local DNA accessibility of synthesized oligonucleotide DNA sequence libraries. (A) The MIAA library sequence construct contains a variable DNA sequence, homology arms for CRISPR-mediated HDR integration at a specific genomic locus that includes...
  6. ...- bisulfite sequencing maps of DNA methylation (Guo et al. 2016; IWGSC 2018; Li et al. 2019; Supplemental Table S1).At the chromosome scale, we observed a strong positive correlation between DMC1 and ASY1 ChIP-seq signals (log2[ChIP/input]) in adjacent 1-Mb windows (-wide Spearman's rs = 0.97), with co...
  7. ...of the gene encoding the spliceosome-associated protein CWC22 (Sharma et al. 2017), not an ancient gene as would be expected if it were the ancestral male-determining locus of brachycerans. Mdmd has been mapped to the autosomes as well as the Y Chromosome (Sharma et al. 2017), suggesting that the house fly Y...
  8. ...and understanding of the vast troves of existing functional genomics and epigenomics data for K562. We performed and integrated deep-coverage whole- (short-insert), mate-pair, and linked-read sequencing as well as karyotyping and array CGH analysis to identify a wide spectrum of characteristics in K562: copy...
  9. ...et al. 2014; Tirosh et al. 2016a). These studies identified single cells with large chromosomal arm–level alterations and detected aberrant expression of cellular pathways impacted by genes within these deleted regions (Patel et al. 2014; Tirosh et al. 2016a). It has not been clear, however, whether...
  10. ...to telomeres, as well as to the centromere position, were determined by BAC-pachytene chromosome fluorescence in situ hybridization (FISH). This gave rise to an estimated length ratio of 5.13 for the long arm and 2.9 for the short arm (on the basis of the physical map), which indicates that the short arm...
For checked items

Preprint Server