Searching journal content for articles similar to Pelizzola et al. 18 (10): 1652.

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  1. ...noted that the observed CpG density bias is not unique to the Affymetrix platform, since unamplified MeDIP-enriched fully methylated DNA samples analyzed on a NimbleGen platform (Gal-Yam et al. 2008) also exhibit attenuation over probes with a broad range of GC contents (Supplemental Fig. 6). Since some...
  2. ...imprinting, and tissue-specific gene expression. Sequencing-based DNA methylation profiling provides an unprecedented opportunity to map and compare complete DNA methylomes. This includes one of the most widely applied technologies for measuring DNA methylation: methylated DNA immunoprecipitation followed...
  3. ...heuristics makes WGBS seem straightforward. Similarly, enrichment-based data are also derived from true methylation states. However, current analytical methods for enrichment-based data usually calculate enrichment scores that are indicative of regional DNA methylation levels corrected by local Cp...
  4. ...and Baylin 2007; Irizarry et al. 2009). Furthermore, distinct -wide methylation patterns distinguish different cell-types (Eckhardt et al. 2006; Rakyan et al. 2008). Sequencing-based DNA methylation data are an emerging technology for analyzing epigenetic modifications (Laird 2010). Methylated DNA...
  5. ...disomy (UPD) provides a system that allows the two parental chromosomes to be studied independently. We profiled the paternal and maternal methylation on chromosome 15 using immunoprecipitation of methylated DNA and hybridization to tiling oligonucleotide arrays. Comparison of six individuals...
  6. ...of -wide promoter methylation We performed comprehensive DNA methylation profiling of gene promoters in normal newborn and adult melanocytes and eight melanoma cell strains (Table 1). DNAmethylation was determined using MeDIP (Weber et al. 2005) followed by hybridization to NimbleGen tiling microarray...
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