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  1. .... Abstract The spontaneously hypertensive rat (SHR) is the most widely studied animal model of hypertension. Scores of SHR quantitative loci (QTLs) have been mapped for hypertension and other phenotypes. We have sequenced the SHR/OlaIpcv genome at 10.7-fold coverage by paired-end sequencing on the Illumina...
  2. ...) investigated APOBEC editing activity in general, which includes all the differentAPOBEC gene variants in humans, in the present study, we looked specifically at edited sites with significant edQTL at the Apobec1 locus. It may well be that Apobec1 expression determines its editing activity...
  3. ...al. 2004 ). The cloning of the Cd36 gene is one of the first examples of cloning a complex trait gene in the rat using a combined approach of introgressing a QTL to generate congenic strains and profiling their expression patterns compared to the parental strain. A more recent study looked at gene...
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