Searching journal content for articles similar to Payen et al. 19 (10): 1710.

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  1. ...Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus Nikolaos Vakirlis 1 , 6 , Véronique Sarilar 2 , 6 , Guénola Drillon 1 , 6 , Aubin Fleiss 1 , Nicolas Agier...
  2. ...relationship between sensu stricto yeast species (not to scale). (B) Schematic of S. cerevisiae chromosome 6 illustrating the location of replication origins (origins represented by circles; circle area corresponds to origin efficiency in W303; later origin activation time is represented by darker shading...
  3. ...Corresponding author: wilsonte@umich.edu Abstract Copy number variants (CNVs) resulting from genomic deletions and duplications and common fragile sites (CFSs) seen as breaks on metaphase chromosomes are distinct forms of structural chromosome instability precipitated by replication inhibition...
  4. ...and heterochromatin. One of the first wide replication timing studies in a metazoan identified broad early and late replicating domains (>100 kb) across the euchromatic portion of theDrosophila chromosome arms (Schubeler et al. 2002). A significant correlation between gene expression and time of replication...
  5. ...of constitutive heterochromatin. Surprisingly, however, regions with high levels of interspersed repeats on the chromosomal arms, in particular on chromosome 4 and in pericentromeric regions of chromosome 2, behave differently. Here, loss of HP1 results in delayed replication. The fact that these regions...
  6. ...in recombination ( Kraus et al. 2001 ). It is a DSB repair process in which the broken chromosome end invades another chromosome or chromatid based on only a few nucleotides of homology and replicates the sequence from there on. BIR was initially reported in yeast to repair unprotected or elongate shortened...
  7. ...of the . This heterogeneity is studied in detail in a separate work (Payen et al. 2009). In brief, it is found that the GC-rich chromosomal segment shows conserved synteny with K. thermotolerans, is devoid of transposable elements, and replicates later than other chromosomes during the S phase. The protoploid yeast species...
  8. ...the potential for other tandem repeat sequences to cause chromosome fragility. Long CTG•CAG repeats are fragile in yeast ( Freudenreich et al. 1998 ). However, no agent has yet been identified that induces fragility of these repeats in human cells, and whether, in fact, they are fragile in mammalian cells...
  9. ...Structure of Chromosomal Duplicons and their Role in Mediating Human Genomic Disorders Yonggang Ji 1 , Evan E. Eichler , Stuart Schwartz , and Robert D. Nicholls 2 Department of Genetics, Case Western Reserve University School of Medicine...
  10. ...between the number of crossovers detected and the number of available SNP markers in a chromosome arm (P-value = 0.126; Supplemental Fig. S8), suggesting our ability to detect crossovers is not strongly affected by variation in the number of SNPs.View larger version: In this window In a new window Figure...
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