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Payen et al. 19 (10): 1710
.
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14
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Research
:
Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus
Nikolaos Vakirlis
,
Véronique Sarilar
,
Guénola Drillon
,
Aubin Fleiss
,
Nicolas Agier
,
Jean-Philippe Meyniel
,
Lou Blanpain
,
Alessandra Carbone
,
Hugo Devillers
,
Kenny Dubois
,
Alexandre Gillet-Markowska
,
Stéphane Graziani
,
Nguyen Huu-Vang
,
Marion Poirel
,
Cyrielle Reisser
,
Jonathan Schott
,
Joseph Schacherer
,
Ingrid Lafontaine
,
Bertrand Llorente
,
Cécile Neuvéglise
,
and
Gilles Fischer
Genome Res.
July 2016
26
:
918
-
932
;
Published in Advance
May 31, 2016
,
doi:
10.1101/gr.204420.116
...Reconstruction of ancestral
chromosome
architecture and gene repertoire reveals principles of genome evolution in a model
yeast
genus Nikolaos Vakirlis 1 , 6 , Véronique Sarilar 2 , 6 , Guénola Drillon 1 , 6 , Aubin Fleiss 1 , Nicolas Agier...
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:
Conservation of replication timing reveals global and local regulation of replication origin activity
Carolin A. Müller
and
Conrad A. Nieduszynski
Genome Res.
October 2012
22
:
1953
-
1962
;
Published in Advance
July 5, 2012
,
doi:
10.1101/gr.139477.112
...relationship between sensu stricto
yeast
species (not to scale). (B) Schematic of S. cerevisiae
chromosome
6 illustrating the location of
replication
origins (origins represented by circles; circle area corresponds to origin efficiency in W303; later origin activation time is represented by darker shading...
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Research
:
Large transcription units unify copy number variants and common fragile sites arising under replication stress
Thomas E. Wilson
,
Martin F. Arlt
,
So Hae Park
,
Sountharia Rajendran
,
Michelle Paulsen
,
Mats Ljungman
,
and
Thomas W. Glover
Genome Res.
February 2015
25
:
189
-
200
;
Published in Advance
November 4, 2014
,
doi:
10.1101/gr.177121.114
...Corresponding author: wilsonte@umich.edu Abstract Copy number variants (CNVs) resulting from genomic deletions and duplications and common fragile sites (CFSs) seen as breaks on metaphase
chromosomes
are distinct forms of structural
chromosome
instability precipitated by
replication
inhibition...
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Research
:
DNA replication and transcription programs respond to the same chromatin cues
Yoav Lubelsky
,
Joseph A. Prinz
,
Leyna DeNapoli
,
Yulong Li
,
Jason A. Belsky
,
and
David M. MacAlpine
Genome Res.
July 2014
24
:
1102
-
1114
;
Published in Advance
July 1, 2014
,
doi:
10.1101/gr.160010.113
...and heterochromatin. One of the first wide
replication
timing studies in a metazoan identified broad early and late
replicating
domains (>100 kb) across the euchromatic portion of theDrosophila
chromosome
arms
(Schubeler et al. 2002). A significant correlation between gene expression and time of
replication
...
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Research
:
Heterochromatin protein 1 (HP1) modulates replication timing of the
Drosophila
genome
Michaela Schwaiger
,
Hubertus Kohler
,
Edward J. Oakeley
,
Michael B. Stadler
,
and
Dirk Schübeler
Genome Res.
June 2010
20
:
771
-
780
;
Published in Advance
April 30, 2010
,
doi:
10.1101/gr.101790.109
...of constitutive heterochromatin. Surprisingly, however, regions with high levels of interspersed repeats on the
chromosomal
arms
, in particular on
chromosome
4 and in pericentromeric regions of
chromosome
2, behave differently. Here, loss of HP1 results in
delayed
replication
. The fact that these regions...
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LETTER
:
Nonrecurrent
MECP2
duplications mediated by genomic architecture-driven DNA breaks and break-induced replication repair
Marijke Bauters
,
Hilde Van Esch
,
Michael J. Friez
,
Odile Boespflug-Tanguy
,
Martin Zenker
,
Angela M. Vianna-Morgante
,
Carla Rosenberg
,
Jaakko Ignatius
,
Martine Raynaud
,
Karen Hollanders
,
Karen Govaerts
,
Kris Vandenreijt
,
Florence Niel
,
Pierre Blanc
,
Roger E. Stevenson
,
Jean-Pierre Fryns
,
Peter Marynen
,
Charles E. Schwartz
,
and
Guy Froyen
Genome Res.
June 2008
18
:
847
-
858
;
Published in Advance
April 2, 2008
,
doi:
10.1101/gr.075903.107
...in recombination ( Kraus et al. 2001 ). It is a DSB repair process in which the broken
chromosome
end invades another
chromosome
or chromatid based on only a few nucleotides of homology and
replicates
the sequence from there on. BIR was initially reported in
yeast
to repair unprotected or elongate shortened...
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Article
:
Comparative genomics of protoploid
Saccharomycetaceae
The Génolevures Consortium
,
Jean-Luc Souciet
,
Bernard Dujon
,
Claude Gaillardin
,
Mark Johnston
,
Philippe V. Baret
,
Paul Cliften
,
David J. Sherman
,
Jean Weissenbach
,
Eric Westhof
,
Patrick Wincker
,
Claire Jubin
,
Julie Poulain
,
Valérie Barbe
,
Béatrice Ségurens
,
François Artiguenave
,
Véronique Anthouard
,
Benoit Vacherie
,
Marie-Eve Val
,
Robert S. Fulton
,
Patrick Minx
,
Richard Wilson
,
Pascal Durrens
,
Géraldine Jean
,
Christian Marck
,
Tiphaine Martin
,
Macha Nikolski
,
Thomas Rolland
,
Marie-Line Seret
,
Serge Casarégola
,
Laurence Despons
,
Cécile Fairhead
,
Gilles Fischer
,
Ingrid Lafontaine
,
Véronique Leh
,
Marc Lemaire
,
Jacky de Montigny
,
Cécile Neuvéglise
,
Agnès Thierry
,
Isabelle Blanc-Lenfle
,
Claudine Bleykasten
,
Julie Diffels
,
Emilie Fritsch
,
Lionel Frangeul
,
Adrien Goëffon
,
Nicolas Jauniaux
,
Rym Kachouri-Lafond
,
Célia Payen
,
Serge Potier
,
Lenka Pribylova
,
Christophe Ozanne
,
Guy-Franck Richard
,
Christine Sacerdot
,
Marie-Laure Straub
,
and
Emmanuel Talla
Genome Res.
October 2009
19
:
1696
-
1709
;
Published in Advance
June 12, 2009
,
doi:
10.1101/gr.091546.109
...of the . This heterogeneity is studied in detail in a separate work (Payen et al. 2009). In brief, it is found that the GC-rich
chromosomal
segment shows conserved synteny with K. thermotolerans, is devoid of transposable elements, and
replicates
later than other
chromosomes
during the S phase. The protoploid
yeast
species...
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REVIEW
:
The biological effects of simple tandem repeats: Lessons from the repeat expansion diseases
Karen Usdin
Genome Res.
July 2008
18
:
1011
-
1019
;
doi:
10.1101/gr.070409.107
...the potential for other tandem repeat sequences to cause
chromosome
fragility. Long CTG•CAG repeats are fragile in
yeast
( Freudenreich et al. 1998 ). However, no agent has yet been identified that induces fragility of these repeats in human cells, and whether, in fact, they are fragile in mammalian cells...
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REVIEW
:
Structure of Chromosomal Duplicons and their Role in Mediating Human Genomic Disorders
Yonggang Ji
,
Evan E. Eichler
,
Stuart Schwartz
,
and
Robert D. Nicholls
Genome Res.
May 1, 2000
10
:
597
-
610
;
doi:
10.1101/gr.10.5.597
...Structure of
Chromosomal
Duplicons and their Role in Mediating Human Genomic Disorders Yonggang Ji 1 , Evan E. Eichler , Stuart Schwartz , and Robert D. Nicholls 2 Department of Genetics, Case Western Reserve University School of Medicine...
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Research
:
Variation in mutation, recombination, and transposition rates in
Drosophila melanogaster
and
Drosophila simulans
Yiguan Wang
,
Paul McNeil
,
Rashidatu Abdulazeez
,
Marta Pascual
,
Susan E. Johnston
,
Peter D. Keightley
,
and
Darren J. Obbard
Genome Res.
April 2023
33
:
587
-
598
;
Published in Advance
April 10, 2023
,
doi:
10.1101/gr.277383.122
...between the number of crossovers detected and the number of available SNP markers in a
chromosome
arm
(P-value = 0.126; Supplemental Fig. S8), suggesting our ability to detect crossovers is not strongly affected by variation in the number of SNPs.View larger version: In this window In a new window Figure...
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