Searching journal content for articles similar to Park and Cenik 35 (4): 999.

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  1. Perspective: Unraveling the hidden complexity of cancer through long-read sequencing
    • Qiuhui Li,
    • Ayse G. Keskus,
    • Justin Wagner,
    • Michal B. Izydorczyk,
    • Winston Timp,
    • Fritz J. Sedlazeck,
    • Alison P. Klein,
    • Justin M. Zook,
    • Mikhail Kolmogorov,
    • and Michael C. Schatz
    Genome Res. April 2025 35: 599-620; Published in Advance March 20, 2025, doi:10.1101/gr.280041.124
    ...exon 1 of the APC gene (Fig. 2D). RNA-seq analysis revealed a substantial decrease in APC expression in the tumor sample (tumor fragments per kilobase of transcript per million fragments mapped (FPKM): 0.296 vs. normal FPKM: 2.262). The SV was not detected by short-read sequencing, likely because...
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  2. Review: Navigating the landscape of epitranscriptomics and host immunity
    • Elaine Huang,
    • Clara Frydman,
    • and Xinshu Xiao
    Genome Res. April 2024 34: 515-529; Published in Advance May 3, 2024, doi:10.1101/gr.278412.123
    ...of immunogenic RNAs, regulation of genes involved in innate immune response, and facilitation of adaptive immunity. Given extensive evidence for their immune relevance, we focus on reviewing the contributions of the following internal (non-cap) host RNA modifications: N6-methyladenosine (m6A), 5-methylcytosine...
  3. Editorial: Long reads decipher genomes and transcriptomes and offer novel insights into biology and diseases
    • Ana Conesa,
    • Alexander Hoischen,
    • and Fritz J. Sedlazeck
    Genome Res. April 2025 35: xi-xiv; doi:10.1101/gr.280665.125
    ...transcripts. Park and Cenik (2025) leverage long-read RNA-seq to reveal allele-specific N6-methyladenosine (m6A) modifications in human and mouse cells, uncovering sequence determinants of m6A deposition. Murali et al. (2025) develop Biosurfer, a computational tool for tracking regulatory mechanisms leading...
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