Searching journal content for articles similar to Pacis et al. 25 (12): 1801.

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  1. Method: Uncovering methylation-dependent genetic effects on regulatory element function in diverse genomes
    • Rachel M. Petersen,
    • Christopher M. Vockley,
    • and Amanda J. Lea
    Genome Res. August 2025 35: 1781-1793; Published in Advance July 14, 2025, doi:10.1101/gr.279957.124
    ...of identifying methylation-dependent regulatory activity at many thousands of genomic regions simultaneously and allows for the testing of causal relationships between DNA methylation and gene expression on a region-by-region basis. Here, we develop a multiplexed mSTARR-seq protocol to assay naturally occurring...
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  2. Method: High-throughput characterization of genetic effects on DNA–protein binding and gene transcription
    • Cynthia A. Kalita,
    • Christopher D. Brown,
    • Andrew Freiman,
    • Jenna Isherwood,
    • Xiaoquan Wen,
    • Roger Pique-Regi,
    • and Francesca Luca
    Genome Res. November 2018 28: 1701-1708; Published in Advance September 25, 2018, doi:10.1101/gr.237354.118
    ...Isaac JL, Yotova V, Dumaine A, Danckaert A, Luca F, Grenier JC, et al. 2015. Bacterial infection remodels the DNA methylation landscape of human dendritic cells. Genome Res 25: 1801–1811. ↵Papadakis KA, Zhu D, Prehn JL, Landers C, Avanesyan A, Lafkas G, Targan SR. 2005. Dominant role for TL1A/DR3 pathway...
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  3. Resource: Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging
    • Jacob C. Kimmel,
    • Lolita Penland,
    • Nimrod D. Rubinstein,
    • David G. Hendrickson,
    • David R. Kelley,
    • and Adam Z. Rosenthal
    Genome Res. December 2019 29: 2088-2103; Published in Advance November 21, 2019, doi:10.1101/gr.253880.119
    ...and cells (Drigo et al. 2019). Studies of DNA methylation patterns with aging also suggest that different tissues age in unique ways (Horvath 2013). However, the cellular origins of aging phenotypes within a tissue remain largely unknown (Rodwell et al. 2004; O'Brown et al. 2015; Benayoun et al. 2019...
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