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Methods: Predicting tissue-specific enhancers in the human genome
- Len A. Pennacchio,
- Gabriela G. Loots,
- Marcelo A. Nobrega,
- and Ivan Ovcharenko
Genome Res. February 2007 17: 201-211; Published in Advance January 8, 2007, doi:10.1101/gr.5972507
...window Figure 3. EI annotation of TNNC1 skeletal muscle ( A ) and APOB ( B ) liver enhancer. Zoomed-in view of Mulan ( Ovcharenko et al. 2005 ) human/mouse evolutionary conservation profiles for these loci depicts candidate enhancer elements, followed by profile of conserved TFBS present within...
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ARTICLE: Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
- Adam Siepel,
- Gill Bejerano,
- Jakob S. Pedersen,
- Angie S. Hinrichs,
- Minmei Hou,
- Kate Rosenbloom,
- Hiram Clawson,
- John Spieth,
- LaDeana W. Hillier,
- Stephen Richards,
- George M. Weinstock,
- Richard K. Wilson,
- Richard A. Gibbs,
- W. James Kent,
- Webb Miller,
- and David Haussler
Genome Res. August 2005 15: 1034-1050; Published in Advance July 15, 2005, doi:10.1101/gr.3715005
...evolving under some reasonable model of neutral evolution are likely to have critical functional roles. Thanks to a recent explosion in the number of sequenced s, and to the development of tools that allow whole s to be aligned ( Brudno et al. 2003 ; Blanchette et al. 2004 ; Bray and Pachter 2004 ), cross...

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