Searching journal content for articles similar to O'Brien et al. 13 (6a): 1029.

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  1. Method: Long-read single-molecule maps of the functional methylome
    • Hila Sharim,
    • Assaf Grunwald,
    • Tslil Gabrieli,
    • Yael Michaeli,
    • Sapir Margalit,
    • Dmitry Torchinsky,
    • Rani Arielly,
    • Gil Nifker,
    • Matyas Juhasz,
    • Felix Gularek,
    • Miguel Almalvez,
    • Brandon Dufault,
    • Sreetama Sen Chandra,
    • Alexander Liu,
    • Surajit Bhattacharya,
    • Yi-Wen Chen,
    • Eric Vilain,
    • Kathryn R. Wagner,
    • Jonathan Pevsner,
    • Jeff Reifenberger,
    • Ernest T. Lam,
    • Alex R. Hastie,
    • Han Cao,
    • Hayk Barseghyan,
    • Elmar Weinhold,
    • and Yuval Ebenstein
    Genome Res. April 2019 29: 646-656; Published in Advance March 7, 2019, doi:10.1101/gr.240739.118
    ...hundreds of kilobase pairs. The method provides kilobase pair–scale genomic methylation patterns comparable to whole- bisulfite sequencing (WGBS) along genes and regulatory elements. These long single-molecule reads allow for methylation variation calling and analysis of large structural aberrations...
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  2. REVIEW: Locating mammalian transcription factor binding sites: A survey of computational and experimental techniques
    • Laura Elnitski,
    • Victor X. Jin,
    • Peggy J. Farnham,
    • and Steven J.M. Jones
    Genome Res. December 2006 16: 1455-1464; Published in Advance October 19, 2006, doi:10.1101/gr.4140006
    ...binding sites in vertebrate genomes. Precise detection of these elements is a prerequisite to deciphering the complex regulatory networks that direct tissue specific and lineage specific patterns of gene expression. This review summarizes approaches for in silico, in vitro, and in vivo identification...
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