Searching journal content for articles similar to Ness et al. 25 (11): 1739.

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  1. ...for the discovery of structural variation (Rhoads and Au 2015; Jain et al. 2018; Mahmoud et al. 2019; Miga et al. 2020; De Coster et al. 2021). These advances now enable the study of the complete spectra of SMs in MA lines. The single-celled green alga Chlamydomonas reinhardtii is an excellent model for mutation...
  2. .... The landscape of the ensuing rearrangements is not accessible by short-read sequencing. Here, we leverage Oxford Nanopore Technologies long-read sequencing to survey the extensive repertoire of rearrangements in telomerase mutants of the model green microalga Chlamydomonas reinhardtii. In telomerase...
  3. ...of this variation is fundamental for parameterizing models of evolution. Here, we provide direct estimates of mutation, recombination, and transposition rates and their variation in a West African and a European population of D. melanogaster and a European population of D. simulans. Across 89 flies, we observe 58...
  4. ...evolution of genes in avian s. Genome Biol 11: R68. Ness RW, Morgan AD, Vasanthakrishnan RB, Colegrave N, Keightley PD. 2015. Extensive de novo mutation rate variation between individuals and across the of Chlamydomonas reinhardtii. Genome Res 25: 1739–1749. Ossowski S, Schneeberger K, Lucas-Lledó JI...
  5. ...et al. 2010). Similarly, the model microalga Chlamydomonas reinhardtii has a core circadian clock and 80% of its genes cycle in a TOD fashion (Zones et al. 2015). In contrast, multicellular, multiorgan plants tested under the LDHH condition have a higher number of cycling genes, such as Arabidopsis...
  6. ...for Evolutionary Biology, 24306 Plön, Germany Corresponding author: elcortegano@protonmail.comAbstractAll forms of genetic variation originate from new mutations, making it crucial to understand their rates and mechanisms. Here, we use long-read sequencing from Pacific Biosciences (PacBio) to investigate de novo...
  7. .... Mutations are underscored. Dharia et al. 1536 Genome Research www..org Indeed, previous work has shown that up to 90% of the existing variation in unique coding regions can be detected using our array (Dharia et al. 2009), and this array has been used to successfully discover newly emerged SNPS in the P...
  8. ...based on indirect inference from species divergence and polymorphism (Washietl et al. 2008; Sasaki et al. 2009; Ying et al. 2010). We observed directly extensive variation across the in the mutation rate and mutation spectra owing to chromatin modifications. In N. crassa, H3K9 trimethylation determines...
  9. ...positioning of chromosomes during cell division and breakage owing to shearing or mechanical stresses. Genome elimination has been achieved by crossing lines carrying point CENH3 mutations in Arabidopsis (Karimi-Ashtiyani et al. 2015; Kuppu et al. 2015), by -editing to produce frameshifts in CENH3 tail...
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  10. ...in offspring after parent irradiation (Adewoye et al. 2015). Even scarcer are genomic approaches that utilize MA experiments to assess the variation in mutation rates across environments after multiple generations. MA experiments have revealed that a stressful high temperature increased the rate of short...
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