Searching journal content for articles similar to Nagy and Bennetzen 18 (12): 1918.

Displaying results 1-10 of 6177

For checked items

view abstracts
download to citation manager

Select this article
Research: Lambdoid phages with abundant Chi recombination hotspots reflect diverse viral strategies for recombination-dependent growth
- Clarence Zheng,
- Sherwood R. Casjens,
- Alan R. Davidson,
- Susan K. Amundsen,
- and Gerald R. Smith
Genome Res. August 2025 35: 1767-1780; Published in Advance July 10, 2025, doi:10.1101/gr.280248.124
...to homologous recombination genes and Chi site distributions in other lambdoid phages. Each of the early left operons in the well-studied lambdoid phages λ, P22, and HK620 and the defective Rac prophage in E. coli K-12 contains a contiguous cluster of homologous recombination genes (Rec modules) (Fig. 2; Table...
OPEN ACCESS ARTICLE
Select this article
Method: Gene duplication is associated with gene diversification and potential neofunctionalization in lung cancer evolution
- Paul Ashford,
- Alexander M. Frankell,
- Zofia Piszka,
- Camilla S.M. Pang,
- Mahnaz Abbasian,
- Maise Al Bakir,
- Mariam Jamal-Hanjani,
- Nicholas McGranahan,
- Charles Swanton,
- and Christine A. Orengo
Genome Res. March 2026 36: 561-577; Published in Advance February 19, 2026, doi:10.1101/gr.278663.123
...than half were in known cancer genes (46%, n = 35/76 postduplication FIEs). Although fewer postduplication FIEs were found in known cancer genes, there was no significant difference in the predicted pathogenicity scores compared with preduplication (CADD [Rentzsch et al. 2019], P = 0.6185; Poly...
OPEN ACCESS ARTICLE
Select this article
Resource: Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease
- Kangli Wang,
- Weikun Xia,
- Yingli Gu,
- Songpeng Zu,
- Qian Yang,
- Maria Luisa Amaral,
- Yaozhi Wang,
- Allen Wang,
- Xiang-Dong Fu,
- William C. Mobley,
- and Bing Ren
Genome Res. April 2026 36: 849-864; Published in Advance March 4, 2026, doi:10.1101/gr.281113.125
...downregulated DEGs were enriched in cell adhesion molecules pathways (Supplemental Fig. S5H).To explore the dynamics of gene expression changes with age, we performed clustering analysis of DEGs, identifying distinct groups with varied functions. In oligodendrocytes, for example, we identified four DEG groups...
OPEN ACCESS ARTICLE
Select this article
Research: Synergistic regulation by H3K36 and H3K27 methylation defines the chromatin landscape to control virulence and secondary metabolism in a fungal pathogen
- Xingmin Han,
- Chenghui Xu,
- Yiyi Ren,
- Meiling Guo,
- Jiayue Yan,
- Xuan Wang,
- Chao Liu,
- Qin Gu,
- Xing-Xing Shen,
- Zhonghua Ma,
- and Yun Chen
Genome Res. November 2025 35: 2472-2487; Published in Advance October 14, 2025, doi:10.1101/gr.280560.125
...proteins in Fusarium graminearum, a globally significant fungal pathogen, reveals diverse roles in growth, development, and virulence. In-depth analyses of two H3K36-specific methyltransferases, Set2 and Ash1, uncover their distinct regulatory functions. Set2-mediated H3K36me3 is enriched in gene bodies...
Select this article
Resource: Cell type–specific gene regulatory atlas prioritizes drug targets and repurposable medicines in Alzheimer's disease
- Yunxiao Ren,
- Ming Hu,
- Yang E. Li,
- Andrew A. Pieper,
- Jeffrey Cummings,
- and Feixiong Cheng
Genome Res. March 2026 36: 645-659; Published in Advance January 21, 2026, doi:10.1101/gr.280436.125
...Cell type–specific gene regulatory atlas prioritizes drug targets and repurposable medicines in Alzheimer's disease Yunxiao Ren1,2, Ming Hu3,4, Yang E. Li5, Andrew A. Pieper6,7,8,9,10,11, Jeffrey Cummings12 and Feixiong Cheng1,2,4,13 1Cleveland Clinic Genome Center, Cleveland Clinic Research...
OPEN ACCESS ARTICLE
Select this article
Research: Unexpectedly low recombination rates and presence of hotspots in termite genomes
- Turid Everitt,
- Tilman Rönneburg,
- Daniel Elsner,
- Anna Olsson,
- Yuanzhen Liu,
- Tuuli Larva,
- Judith Korb,
- and Matthew T. Webster
Genome Res. May 2025 35: 1124-1137; Published in Advance March 20, 2025, doi:10.1101/gr.279180.124
...by pathogens or parasites owing to diversification of immune genes (Fischer and Schmid-Hempel 2005). Recombination could also reduce variance in relatedness between nestmates, thereby reducing potential kin conflict within colonies (Sherman 1979; Templeton 1979; Wilfert et al. 2007). Additionally, it has been...
Select this article
Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
- Andrew D. Bates,
- Dawid Grzela,
- Maciej Studzian,
- Louise Brennan,
- Moli Williams,
- Conor Fawcett,
- Beth Hammond,
- Manreen Grewal,
- Marcin Ratajewski,
- Lukasz Pulaski,
- and Urszula L. McClurg
Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
...-scanning, or site-directed mutagenesis. These approaches enable precise mapping of essential cis-elements, such as promoters, enhancers, and TF binding sites, by directly testing the impact of sequence alterations on transcriptional activity.Data mining -wide studiesAlthough computational prediction alone cannot...
OPEN ACCESS ARTICLE
Select this article
Mini-Review: The paradox of R-loops: guardians of the genome or drivers of disease?
- Shachinthaka D. Dissanayaka Mudiyanselage,
- Phillip Wulfridge,
- and Kavitha Sarma
Genome Res. September 2025 35: 1919-1928; Published in Advance August 6, 2025, doi:10.1101/gr.278992.124
...aberrant accumulation and excessive removal of R-loops result in increased levels of readthrough RNA. Therefore, dysregulation of R-loops at gene ends could result in termination defects that lead to pathogenic misexpression of genes. For example, readthrough transcripts have been detected in cancer...
Select this article
Method: Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation
- Sophia N. Lee,
- Erin C. Banda,
- Lu Qiao,
- Sarah L. Thompson,
- Karan Singh,
- Ryan A. Hagenson,
- Teresa Davoli,
- Stefan F. Pinter,
- and Jason M. Sheltzer
Genome Res. March 2026 36: 547-560; Published in Advance January 12, 2026, doi:10.1101/gr.280425.125
...gene receptor clusters found within this region (Giglio et al. 2001). Individuals affected by 8p syndrome present with a variety of clinical phenotypes, including agenesis of the corpus callosum, epilepsy, and other neurodevelopmental delays (Vibert et al. 2022).Over the past several decades...
Select this article
Method: Highly efficient and scarless genome editing via essential gene-coupled homology-directed repair
- Joo Hye Yeo,
- Hyongbum Henry Kim,
- Sang Ho Oh,
- and Jinu Lee
Genome Res. April 15, 2026 gr.281194.125; Published in Advance April 15, 2026, doi:10.1101/gr.281194.125
..., including disease modeling (Platt et al. 2014; Paquet et al. 2016; 56 Bu et al. 2023), gene function analysis (Hu et al. 2022; Hu et al. 2024), and precision 57 gene therapy (Catto and Dunbar 2024; Liao et al. 2024). However, in most mammalian 58 cells, double-strand breaks (DSBs) induced by programmable...
- Abstract
- Full Text (PDF)
ACCEPTED MANUSCRIPT

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Nagy and Bennetzen 18 (12): 1918.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: