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  1. ...and Viral Translation Team, Université de Lyon, INSERM U1111, Lyon, 69634, France Elucidating the consequences of genetic differences between humans is essential for understanding phenotypic diversity and personalized medicine. Although variation in RNA levels, transcription factor binding, and chromatin...
  2. ...are also amplified in every CNV strain. As BMH1 only displays increased mutational tolerance in three strains, it is unlikely that the core set of 17 genes in the CNVs underlies this effect.View larger version: In this window In a new window Figure 3. CNV strains have common and allele-specific genetic...
  3. ...of genes (Fig. 1; Bullard et al. 2010; Fraser et al. 2010, 2011; Fraser 2011). Input for the test is -wide allele-specific expression (ASE) data from a hybrid between two diverged lineages (denoted A and B) and a catalog of gene sets to be tested (sets can be based on any type of relationship, e.g., shared...
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