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  1. ...domain. We demonstrate that the latter are imprinted and preferentially expressed from the maternal allele. We show that the CLPG mutation affects their level of expression in cis (∼3.2-fold increase) as well as in trans (∼1.8-fold increase). In CLPG/CLPG animals, miRNAs from the DLK1–GTL2...
  2. .... Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. Hum. Mol. Genet. 11 : 1527 -1538. ↵ Charlier, C., Segers, K., Karim, L., Shay, T., Gyapay, G., Cockett, N., and Georges, M. 2001 . The callipyge mutation...
  3. ...by perturbing the expression profile of genes located in cis (standard polygenic model) or, possibly, by perturbing the gene regulatory network and affecting the expression profile of a restricted number of core genes in trans (omnigenic model) (Liu et al. 2019). Regulatory variants are more difficult...
  4. ...) Callipyge mutation affects gene expression in cis: A potential role for chromatin structure . Genome Res. 16 : 340 – 346 . ↵ Nagaki, K. , Cheng, Z. , Ouyang, S. , Talbert, P.B. , Kim, M. , Jones, K.M. , Henikoff, S. , Buell, C.R. , Jiang, J. ( 2004 ) Sequencing of a rice centromere uncovers active genes...
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