Searching journal content for articles similar to Murphy et al. 13 (8): 1880.

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  1. ...conservation does not fall within the scope of Ohno's original prediction (Ohno 1967) as intrachromosomal rearrangements presumably would not disrupt dosage levels to the same degree as would interchromosomal translocations. Linkage conservation is also not as pervasive as the conservation of gene content...
  2. ..., and Diptera, and the 800 Mb grasshopper X Chromosome is homologous to the fly ancestral X Chromosome despite 400 million years of divergence, suggesting either repeated origin of sex chromosomes with highly similar gene content, or long-term conservation of the X Chromosome. We use this broad conservation...
  3. ...both elephant and non-elephant genes in a phylogenetic gene tree of a candidate OGG. If a clade contained elephant genes and genes from other species, those elephant and non-elephant genes were likely tohave originated froma single ancestral gene in the MRCA of placental mammals, and therefore...
  4. ...in female heterogametic systems.Chromosomal sex determination is widespread in animals, having originated multiple times in different lineages (for reviews, see Bachtrog et al. 2014; Graves 2016). For example, birds have a female-heterogametic sex chromosome system in which males are homozygous for the Z...
  5. .... Origins and functional evolution of Y chromosomes across mammals. Nature 508: 488–493. doi:10.1038/nature13151 ↵Davis BW, Seabury CM, Brashear WA, Li G, Roelke-Parker M, Murphy WJ. 2015. Mechanisms underlying mammalian hybrid sterility in two feline interspecies models. Mol Biol Evol 32: 2534–2546. doi:10...
  6. ...to the mammalian or avian sex chromosomes have undergone significant changes in gene dosage. In modern mammals, these molecular events have resulted in three classes of ancestral X-linked genes representing distinct evolutionary fates: those with a surviving Y homolog, those with no Y homolog and subject to XCI...
  7. ...Phylogenetic Origin of Human Chromosomes 7, 16, and 19 and their Homologs in Placental Mammals Florence Richard 1 , 2 , 4 , Martine Lombard 1 , and Bernard Dutrillaux 1 , 3 1Unité Mixte de Recherche (UMR) 147 Centre National de Recherche...
  8. ...chromosome 19p13 fragment. (**) The co-orthologous relationship of the zebrafish RFLC2 gene on chromosome 24 to the pufferfish counterparts was determined based on sequence similarity analysis. INSL3 is a therian mammal-specific signature protein In addition to revealing the origin of relaxin family genes...
  9. ..., with 73% of lincRNAs in cow, 58% in mouse, and 54% in rat, showing >30% exonic alignment. This fraction is well below that of mRNAs but clearly above random regions (Table 1; Supplemental Fig. 3). LincRNA expression across mammals To detect the expression of homologous lincRNAs in other species, we...
  10. ...chromosomes, and expression was exclusively from the inactive (paternal) X chromosome. Our study provides the first comprehensive catalog of parent-of-origin expression status for X-linked genes in a marsupial and sheds light on the regulation and evolution of imprinted XCI in mammals. [Supplemental material...
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