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  1. ...portion of BTA28. A different example of change in map resolution is shown on the RH maps of BTA10 and BTA21 that show previously undescribed rearrangements between homologous segments of regions on HSA14 and HSA15. In all, we observed 105 conserved segments with two or more genes and a potential for 149...
  2. ...that of cattle is found at the tip of the long arm. Other differences between ruminant X chromosomes include the relative positions of the centromeres, and the rearrangement of the bovine Xp24–Xq12 and Xq21–Xq24 regions in goats ( Piumi et al. 1998 ). Comparison of the ovine and bovine X chromosome linkage maps...
  3. .... , Craig, I.W. , Boyd. Y. Blair, H.J., Ho, M. Monaco, A.P. Fisher, S. Craig, I.W. and Boyd. Y. 1995 . High-resolution comparative mapping of the proximal region of the mouse X chromosome. Genomics 28 : 305 – 310 . Botstein, D., , White, R.L. , Skolnick, M. , Davis. R.W. Botstein, D., White, R.L. Skolnick...
  4. ...loci, suggesting a possible synteny ( Miles et al. 1998 ; C. Miles and G. Elgar, pers. comm.). The fact that GA17 maps to chromosome X (DXS983–995) according to GeneMap'98 likely results from the presence of a truncated GA17 pseudogene that can be detected in the PAC 849L7 located on Xq21 (Gen...
  5. .... and Sutherland. G.R. 1995 . Integration of transcript and genetic maps of chromosome 16 at near 1 Mb resolution: Demonstration of a hot spot for recombination at 16pl2. Genomics 29 : 503 – 511 . Chen, E., , d'Urso, M. , Schlessinger. D. Chen, E., d'Urso, M. and Schlessinger. D. 1994 . Functional mapping...
  6. ..., although the profile is rather different from that seen for HMEC; (3) the region surrounding the XIC shows a profile similar to that seen innormal cells; and (4) the regionspanningXq21.33 to the end of the long arm, which is no longer linked to the XIC (see Fig. 3), does not display discernable H3K27me3...
  7. ...lines. Schematics of genomic target loci before (top) and after (bottom) HPV integration in HNSCC cell lines (A) UM-SCC-47 and (B) UPCI:SCC090, chromosome 6. Target gene schematic and connectivity map features are as described in the Figure 4 legend. HPV breakpoint numbers are listed in Supplemental...
  8. ...but not necessarily gene order ( Kehrer-Sawatzki et al. 1999 ; Gellner et al. 1999 ), and extensive differences in gene order within regions of conserved synteny ( Gilley et al. 1999 ). One of the Fugu cosmids scanned, 061J03, contains the Fugu ortholg of Bruton's tyrosine kinase gene (BTK), which in man maps to Xq21...
  9. ...distribution (data not shown). We also examined the distribution of [GATA] n at high resolution along the X chromosome by searching for perfect incidences of GATA repeats of any length, rather than nine base words, and creating a physical map (Fig. 6 ). This analysis shows that [GATA] n is present at a large...
  10. ...version: In this window In a new window Figure 4. Paralogy map and sequence content of the HSA5/HSA6 duplicon. The genomic organization of the duplicated region was deduced from the AL157879 and AL133255 clones that were chosen as reference seed sequence. The thick gray lines illustrate the homology...
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