Searching journal content for articles similar to Mularoni et al. 22 (4): 693.

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  1. LETTER: Local Definition of Ty1 Target Preference by Long Terminal Repeats and Clustered tRNA Genes
    • Nurjana Bachman,
    • Yolanda Eby,
    • and Jef D. Boeke
    Genome Res. July 2004 14: 1232-1247; Published in Advance June 14, 2004, doi:10.1101/gr.2052904
    ...and LTRs surrounding the target tDNA dramatically influenced the frequency of insertion events upstream of that target. Ty1 is an LTR retrotransposon in Saccharomyces cerevisiae that integrates specifically into the host and generates target-site duplications. Previous work has shown that the Ty1's...
  2. Method: Unraveling the palindromic and nonpalindromic motifs of retroviral integration site sequences by statistical mixture models
    • Dalibor Miklík,
    • Jiří Grim,
    • Daniel Elleder,
    • and Jiří Hejnar
    Genome Res. August 2023 33: 1395-1408; Published in Advance July 18, 2023, doi:10.1101/gr.277694.123
    ...of the frequently targeted sequences forming local hotspots. We hypothesize that the multicomponent mixture-driven description of tDNA motif/sequence subpopulations will provide novel insight into the preferences in retroviral integration site (IS) selection.ResultsEM algorithm uncovers palindromic and asymmetric...
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  3. Research: Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites
    • Kurt Patterson,
    • Farbod Shavarebi,
    • Christophe Magnan,
    • Ivan Chang,
    • Xiaojie Qi,
    • Pierre Baldi,
    • Virginia Bilanchone,
    • and Suzanne B. Sandmeyer
    Genome Res. August 2019 29: 1298-1309; Published in Advance June 27, 2019, doi:10.1101/gr.240861.118
    ...targets (Supplemental Table S2). Normalized insertion cluster counts for 267 tDNAs ranged from 2.75 ± 0.079 at tE(UUC)P to 112.46 ± 8.69 at CDC65 (Systematic name: tQ(CUG)M). The vast majority of insertions were positioned upstream of tDNAs (encoding mature tRNA sequence) such that the 5-bp Ty3 TSD tDNA...
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