Searching journal content for articles similar to Montibus et al. 34 (12): 2163.

Displaying results 1-4 of 4
For checked items
  1. .... Although most of these gDMRs are erased during the global DNA methylation reprogramming that occurs in preimplantation development (right), ICRs stand out by being protected through the recruitment of ZFP57/ZNF445 and the KRAB-ZNF corepressor complex (left). This protection leads to the maintenance of 20...
  2. ...-regulatory elements, such as enhancers, and thus potentially involved in regulation of tissue-specific gene expression (Pastor et al. 2013; Wu and Zhang 2014). However, how 5hmC regulates and shapes tissue-specific epis through DNA demethylation remains largely unknown. Significant global loss of hydroxymethylation...
  3. ...(seeMethods; Supplemental Fig. 2A).We confirmed circular RNA protection using PCR targeting linear and circular isoformsofMAN1A2andFBXW4genes (Supplemental Fig. 2B,C; Salzman et al. 2012). Digested libraries were sequenced and aligned to the , indicating a global 9.6-fold global enrichment for introns...
  4. .... In parallel, we isolated RNA from S2 cells and generated global gene expression profiles by RNAseq to correlate protein binding with transcriptional activity. Furthermore, we surveyed the Drosophila for nonannotated TSSs using a newly adapted protocol for Illumina sequencing (termed 59-MACE) with RNA isolated...
For checked items

Preprint Server