Searching journal content for articles similar to Mittler et al. 19 (2): 284.

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  1. Method: Quantitative proteomic analysis reveals concurrent RNA–protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae
    • Daniel M. Klass,
    • Marion Scheibe,
    • Falk Butter,
    • Gregory J. Hogan,
    • Matthias Mann,
    • and Patrick O. Brown
    Genome Res. June 2013 23: 1028-1038; Published in Advance May 1, 2013, doi:10.1101/gr.153031.112
    ...diverse, and we mapped the RNA-binding region of one of these proteins, the transcriptional coactivator Mbf1, to a region distinct from its DNA-binding domain. Our results also provided new insights into the roles of Nab2 and Puf3 in post-transcriptional regulation by identifying other RBPs that bind...
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  2. Research: E4F1 and ZNF148 are transcriptional activators of the −57A > C and wild-type TERT promoter
    • Boon Haow Chua,
    • Nurkaiyisah Zaal Anuar,
    • Laure Ferry,
    • Cecilia Domrane,
    • Anna Wittek,
    • Vineeth T. Mukundan,
    • Sudhakar Jha,
    • Falk Butter,
    • Daniel G. Tenen,
    • Pierre-Antoine Defossez,
    • and Dennis Kappei
    Genome Res. November 2023 33: 1893-1905; Published in Advance November 2, 2023, doi:10.1101/gr.277724.123
    ...in vitro. (A) Schematic showing the coverage of the TERT promoter sequence by the DNA probes used in this study. (B) Workflow for a quantitative SILAC-based protein–DNA interaction screen. Biotinylated concatenated DNA oligonucleotides from A were immobilized on magnetic streptavidin beads, and bound...
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  3. Research: Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions
    • Stacey E.P. Joosten,
    • Sebastian Gregoricchio,
    • Suzan Stelloo,
    • Elif Yapıcı,
    • Chia-Chi Flora Huang,
    • Kerim Yavuz,
    • Maria Donaldson Collier,
    • Tunç Morova,
    • Umut Berkay Altintaş,
    • Yongsoo Kim,
    • Sander Canisius,
    • Cathy B. Moelans,
    • Paul J. van Diest,
    • Gozde Korkmaz,
    • Nathan A. Lack,
    • Michiel Vermeulen,
    • Sabine C. Linn,
    • and Wilbert Zwart
    Genome Res. April 2024 34: 539-555; Published in Advance May 6, 2024, doi:10.1101/gr.278680.123
    ...(TF), associating to DNA regulatory elements upon ligand-mediated activation to drive activity of responsive genes, ultimately giving rise to tumor growth. DNA binding sites for ESR1 are enriched for the palindromic DNA sequence AGGTCAnnnTGACCT, termed estrogen response elements (EREs), through which...
  4. Method: P-value-based regulatory motif discovery using positional weight matrices
    • Holger Hartmann,
    • Eckhart W. Guthöhrlein,
    • Matthias Siebert,
    • Sebastian Luehr,
    • and Johannes Söding
    Genome Res. January 2013 23: 181-194; Published in Advance September 18, 2012, doi:10.1101/gr.139881.112
    ...-Maximilians-Universität (LMU) München, Feodor-Lynen-Straße 25, 81377 Munich, Germany Abstract To analyze gene regulatory networks, the sequence-dependent DNA/RNA binding affinities of proteins and noncoding RNAs are crucial. Often, these are deduced from sets of sequences enriched in factor binding sites. Two...
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