Searching journal content for articles similar to Mellis and Raj 25 (10): 1466.

Displaying results 1-10 of 6116
For checked items
  1. Method: ScisTree2 enables large-scale inference of cell lineage trees and genotype calling using efficient local search
    • Haotian Zhang,
    • Yiming Zhang,
    • Teng Gao,
    • and Yufeng Wu
    Genome Res. December 2025 35: 2781-2791; Published in Advance September 3, 2025, doi:10.1101/gr.280542.125
    ...et al. 2017); (iv) the original ScisTree (Wu 2020); and (v) for small data only, SCITE (Jahn et al. 2016). In addition to comparing running time, we used the following metrics (all between 0 and 1, with 1 being the best) for accuracy comparison. Genotype accuracy: the percentage of correctly called...
    OPEN ACCESS ARTICLE
  2. Mini-Review: Large-scale genomic analysis of the domestic dog informs biological discovery
    • Reuben M. Buckley and
    • Elaine A. Ostrander
    Genome Res. June 2024 34: 811-821; Published in Advance July 2, 2024, doi:10.1101/gr.278569.123
    ...genetics: A small number of loci account for a large fraction of phenotypic variance. For instance, fewer than 30 genes are responsible for >80% of the variance in body size across breeds, supporting an earlier study in which variation in just six genes accounted for ∼50% of body size variation (Fig. 1A...
    OPEN ACCESS ARTICLE
  3. Method: High-fidelity, large-scale targeted profiling of microsatellites
    • Caitlin A. Loh,
    • Danielle A. Shields,
    • Adam Schwing,
    • and Gilad D. Evrony
    Genome Res. July 2024 34: 1008-1026; Published in Advance July 16, 2024, doi:10.1101/gr.278785.123
    ...genotyping of microsatellites.Large-scale profiling of microsatellitesAfter developing an optimal probe design strategy and a low-temperature amplification method for reducing stutter with a small-scale pilot panel of loci, we next proceeded to scale our method to a much larger number of microsatellite loci...
  4. Method: Secure discovery of genetic relatives across large-scale and distributed genomic data sets
    • Matthew M. Hong,
    • David Froelicher,
    • Ricky Magner,
    • Victoria Popic,
    • Bonnie Berger,
    • and Hyunghoon Cho
    Genome Res. September 2024 34: 1312-1323; Published in Advance August 7, 2024, doi:10.1101/gr.279057.124
    ...the identity-by-descent (IBD) segments become more scattered and reduced in quantity, which in turn results in a lower rate of surviving the filtering step in microbucketing. In UKB-200K, we observed that a small fraction (5%) of third-degree relatives, missed by SF-Relate, correspond to those with kinship...
    OPEN ACCESS ARTICLE
  5. Research: Large-scale investigation of species-specific orphan genes in the human gut microbiome elucidates their evolutionary origins
    • Nikolaos Vakirlis and
    • Anne Kupczok
    Genome Res. June 2024 34: 888-903; Published in Advance July 8, 2024, doi:10.1101/gr.278977.124
    ...of an alternative reading frame of an existing gene following duplication or HGT. To this end, we performed similarity searches of six-frame translations of all SSOG coding sequences against six-frame translations of all coding sequences of their native . We found that only a small percentage, 1.34% of SSOGs (8477...
  6. Resource: A systems view on DNA damage response kinetics in Tetrahymena
    • Emily Nischwitz,
    • Vivien A.C. Schoonenberg,
    • Rachel Mullner,
    • Albert Fradera-Sola,
    • Susanne Zimbelmann,
    • Joshua J. Smith,
    • and Falk Butter
    Genome Res. January 28, 2026 ; Published in Advance January 28, 2026, doi:10.1101/gr.281000.125
    ...,” “cellular response to DNA damage stimulus,” “DNA replication,” and “DNA metabolic process.” Within the average expression profile for CPT-treated cells in this cluster, there is an immediate strong and continual upregulation until 8 h. This response could be due to the known long half-life of CPT (Evans et...
  7. Method: Large-scale detection and characterization of inter-chromosomal rearrangements in normozoospermic bulls using massive genotype and phenotype data sets
    • Jeanlin Jourdain,
    • Harmonie Barasc,
    • Thomas Faraut,
    • Anne Calgaro,
    • Nathalie Bonnet,
    • Camille Marcuzzo,
    • Amandine Suin,
    • Anne Barbat,
    • Chris Hozé,
    • Florian Besnard,
    • Sébastien Taussat,
    • Cécile Grohs,
    • Claire Kuchly,
    • Carole Iampietro,
    • Cécile Donnadieu,
    • Alain Pinton,
    • Didier Boichard,
    • and Aurélien Capitan
    Genome Res. July 6, 2023 ; Published in Advance July 6, 2023, doi:10.1101/gr.277787.123
    ...-sib families (see Methods) (Fig. 1A). Obviously, these thresholds were higher when the number of offspring was lower and the minimum size of the sire families was set to more than 30 half-siblings. Large-scale screening for IRs In the next step, we analyzed 5571 paternal half-sib families from 15 different...
  8. Method: Analysis of coding gene expression from small RNA sequencing
    • Aygun Azadova,
    • Anthonia Ekperuoh,
    • Greg N. Brooke,
    • and Antonio Marco
    Genome Res. March 2026 36: 611-618; Published in Advance February 10, 2026, doi:10.1101/gr.281364.125
    ...determinant of whether small RNA libraries can be used to successfully measure coding gene expression levels.Transcript half-life has a negligible effect on small RNA expression estimates across tissuesTo evaluate potential biases in the transcript coverage between total and small RNA libraries, we computed...
  9. Method: Fast and accurate out-of-core PCA framework for large scale biobank data
    • Zilong Li,
    • Jonas Meisner,
    • and Anders Albrechtsen
    Genome Res. September 2023 33: 1599-1608; Published in Advance August 24, 2023, doi:10.1101/gr.277525.122
    .... The algorithm terminates when the difference of eigenvectors between two successive epochs is smaller than a user defined threshold (default 1 − MEV < 10−4). This often occurs after six epochs, in which a second update of Ω based on the entire data leads to only a very small change of Ω and thus the estimated...
  10. Research: Low-frequency somatic copy number alterations in normal human lymphocytes revealed by large-scale single-cell whole-genome profiling
    • Lu Liu,
    • He Chen,
    • Cheng Sun,
    • Jianyun Zhang,
    • Juncheng Wang,
    • Meijie Du,
    • Jie Li,
    • Lin Di,
    • Jie Shen,
    • Shuang Geng,
    • Yuhong Pang,
    • Yingying Luo,
    • Chen Wu,
    • Yusi Fu,
    • Zhe Zheng,
    • Jianbin Wang,
    • and Yanyi Huang
    Genome Res. January 2022 32: 44-54; Published in Advance December 28, 2021, doi:10.1101/gr.275453.121
    ...of small CNAs. Therefore, for the lymphocyte samples, we decided to include only CNA calls larger than 2 Mb.Somatic CNA events occurred commonly in lymphocytesWe examined 33,600 single lymphocytes sorted from the blood of 16 cancer-free individuals (10 males and six females; 1440–3840 single lymphocytes...
    OPEN ACCESS ARTICLE
For checked items

Search Results

Next 10 » New Search

Modify Results

Citation format:
Results / page:
Results order:

This search

  • Alert me when new articles matching this search are published
  • Download all citations on this page to my citation manager

Preprint Server



Current Issue

  1. April 2026, 36 (4)
  1. Current Issue
  1. Alert me to new issues of Genome Research