Searching journal content for articles similar to Melanitou et al. 8 (6): 608.

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  1. ...in the search for genes conferring susceptibility to a complex trait such as diabetes. Rare disease alleles in families from the north and east of Finland travel on haplotypes as large as 15 cM ( de la Chapelle and Wright 1998 ), suggesting that it may be possible to identify diabetes-associated haplotypes...
  2. ...diabetes-associated alleles on the distal part of mouse chromosome 6. Genome Res. 8 : 608 – 620 . ↵ Merriman T. , Twells R. , Merriman M. , Eaves I. , Cox R. , Cucca F. , McKinney P. , Shield J. , Baum D. , Bosi E. , et al. ( 1997 ) Evidence by allelic association-dependent methods for a type 1 diabetes...
  3. ...comprising two or more separable genes) on chromosome 1 affecting early rapid somatic growth, development of early insulin resistance, and maturity-onset diabetes. Another QTL contributing significantly to hyperglycemia also appears to be complex. We previously identified non-insulin-dependent diabetes...
  4. ...markers. METHODS DNA Samples A total of 384 samples were drawn from 96 type 1 diabetic families, part of the British Diabetic Association-Warren repository (Bain et al. 1990). DNA was extracted from Epstein– Barr virus (EBV)-transformed peripheral blood lymphocytes. Briefly, 50 ml of confluent EBV cells...
  5. ...kindly provided reagents, samples, or unpublished information as indicated in the paper: K. Matsumoto and the Sir Frederick Banting Research Centre. Type 1 (insulin dependent) diabetes mellitus in humans is a significant health problem with a prevalence ranging from 0.3% to 1% in different populations...
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