Searching journal content for articles similar to McSweeney et al. 26 (10): 1411.

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  1. Research: Genome-wide, integrative analysis of circular RNA dysregulation and the corresponding circular RNA-microRNA-mRNA regulatory axes in autism
    • Yen-Ju Chen,
    • Chia-Ying Chen,
    • Te-Lun Mai,
    • Chih-Fan Chuang,
    • Yu-Chen Chen,
    • Sachin Kumar Gupta,
    • Laising Yen,
    • Yi-Da Wang,
    • and Trees-Juen Chuang
    Genome Res. March 2020 30: 375-391; Published in Advance March 3, 2020, doi:10.1101/gr.255463.119
    ...-derived organoids show overproduction of inhibitory neurons. We further confirmed that some ASD risk genes (NLGN1, STAG1, HSD11B1, VIP, and UBA6) were regulated by an up-regulated circRNA (circARID1A) via sponging a down-regulated microRNA (miR-204-3p) in human neuronal cells. Particularly, alteration of NLGN1...
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  2. Research: Dynamic modulation of genomic enhancer elements in the suprachiasmatic nucleus, the site of the mammalian circadian clock
    • Akanksha Bafna,
    • Gareth Banks,
    • Michael H. Hastings,
    • and Patrick M. Nolan
    Genome Res. May 2023 33: 673-688; Published in Advance May 8, 2023, doi:10.1101/gr.277581.122
    ...-enriched promoter and enhancer sites marked by H3K4me3 and H3K27ac, respectively. C57BL/6J mice were kept in standard 12-h/12-h light–dark conditions, and eight animals per time point (Methods) were used for subsequent brain dissections. The harvested SCN and cerebral cortical brain regions were then used for H3K4...
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  3. Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
    • Andrew D. Bates,
    • Dawid Grzela,
    • Maciej Studzian,
    • Louise Brennan,
    • Moli Williams,
    • Conor Fawcett,
    • Beth Hammond,
    • Manreen Grewal,
    • Marcin Ratajewski,
    • Lukasz Pulaski,
    • and Urszula L. McClurg
    Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
    ..., hinging on the precise binding of transcription factors (TFs) and cofactors to gene regulatory elements such as promoters and enhancers. Although it is relatively routine to profile -wide DNA binding landscapes of proteins, identifying the specific proteins that bind to, and regulate the transcription of...
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