Searching journal content for articles similar to McGinty et al. 27 (12): 2072.

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  1. Research: The rate and spectrum of new mutations in mice inferred by long-read sequencing
    • Eugenio López-Cortegano,
    • Jobran Chebib,
    • Anika Jonas,
    • Anastasia Vock,
    • Sven Künzel,
    • Peter D. Keightley,
    • and Diethard Tautz
    Genome Res. January 2025 35: 43-54; Published in Advance December 2, 2024, doi:10.1101/gr.279982.124
    ...(Potter et al. 2017). All of these types of SMs emerge predominantly owing to failure of the repair of double-strand breaks and involve mechanisms that typically depend on either homologous recombination or end-joining (So et al. 2017). Thus, chromosome instability and processes such as nonallelic...
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  2. Research: Rates and spectra of de novo structural mutations in Chlamydomonas reinhardtii
    • Eugenio López-Cortegano,
    • Rory J. Craig,
    • Jobran Chebib,
    • Eniolaye J. Balogun,
    • and Peter D. Keightley
    Genome Res. January 2023 33: 45-60; Published in Advance December 12, 2022, doi:10.1101/gr.276957.122
    ...%). In CC-2931, a Crypton and a previously undescribed type of DNA element have caused 71% of chromosomal rearrangements, whereas in CC-1952, a Dualen LINE is associated with 87% of duplications. Other SMs, notably large duplications in CC-2931, are likely products of various double-strand break repair...
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  3. Research: Candida albicans isolates contain frequent heterozygous structural variants and transposable elements within genes and centromeres
    • Ursula Oggenfuss,
    • Robert T. Todd,
    • Natthapon Soisangwan,
    • Bailey Kemp,
    • Alison Guyer,
    • Annette Beach,
    • and Anna Selmecki
    Genome Res. April 2025 35: 824-838; Published in Advance October 22, 2024, doi:10.1101/gr.279301.124
    ...mechanisms, including TE mobilization or homologous repair following DNA-double-stranded breaks (Todd et al. 2019, Berdan et al. 2021).The human fungal pathogen Candida albicans is an asexual diploid organism that displays significant genomic plasticity (Vande Zande et al. 2023). SVs are important drivers...
  4. Research: Genetic variation in recalcitrant repetitive regions of the Drosophila melanogaster genome
    • Harsh G. Shukla,
    • Mahul Chakraborty,
    • and J.J. Emerson
    Genome Res. September 2025 35: 2023-2040; Published in Advance July 16, 2025, doi:10.1101/gr.280728.125
    ....5%) is repetitive, with two repeat elements—LINE R1/R2—dominating the landscape, although R1 is by far the more abundant of the two (Fig. 2B). Further analysis revealed these flanking R1 elements are predominantly fragmented, differing from the intact, full-length R1 sequences observed within the main rDNA array...
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