Searching journal content for articles similar to Mattioli et al. 29 (3): 344.

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  1. Research: Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis
    • Kai Li,
    • Jiayue Xu,
    • Yanyun Luo,
    • Dingfeng Zou,
    • Ruiqin Han,
    • Shunshun Zhong,
    • Qing Zhao,
    • Xinyu Mang,
    • Mengzhen Li,
    • Yanmin Si,
    • Yan Lu,
    • Pengyu Li,
    • Cheng Jin,
    • Zhipeng Wang,
    • Fang Wang,
    • Shiying Miao,
    • Bo Wen,
    • Linfang Wang,
    • Yanni Ma,
    • Jia Yu,
    • and Wei Song
    Genome Res. January 2021 31: 13-26; Published in Advance December 16, 2020, doi:10.1101/gr.264333.120
    ...the cell specificity of six candidate lncRNAs, and the results showed that they were specifically expressed in germ cells (Fig. 2D). We then used qRT-PCR and northern blots to detect the expression of the six lncRNAs across multiple tissues and found that all of them displayed a testis-specific pattern...
  2. Research: Motif conservation, stability, and host gene expression are the main drivers of snoRNA expression across vertebrates
    • Étienne Fafard-Couture,
    • Pierre-Étienne Jacques,
    • and Michelle S. Scott
    Genome Res. April 2023 33: 525-540; Published in Advance April 18, 2023, doi:10.1101/gr.277483.122
    ...). This suggests that the expression of these 10 snoRNAs is greatly favored because GAS5 is a functionally important lncRNA that is thereby expressed in humans and because each of these 10 snoRNAs possesses conserved motifs and a stable terminal stem (Supplemental Table S1). Of note, all of the mentioned host gene...
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  3. Research: The identification and functional annotation of RNA structures conserved in vertebrates
    • Stefan E. Seemann,
    • Aashiq H. Mirza,
    • Claus Hansen,
    • Claus H. Bang-Berthelsen,
    • Christian Garde,
    • Mikkel Christensen-Dalsgaard,
    • Elfar Torarinsson,
    • Zizhen Yao,
    • Christopher T. Workman,
    • Flemming Pociot,
    • Henrik Nielsen,
    • Niels Tommerup,
    • Walter L. Ruzzo,
    • and Jan Gorodkin
    Genome Res. August 2017 27: 1371-1383; Published in Advance May 9, 2017, doi:10.1101/gr.208652.116
    ...in the tissue-specific lncRNA AC073046.25. Thus, our CaptureSeq strategy identified (and qRT-PCR partially validated) conserved expression profiles of CRSs with low abundance and low sequence conservation, leading to putative functional genes. Structure probing shows CRSs in human and mouse...
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  4. Research: Copy number variation underlies complex phenotypes in domestic dog breeds and other canids
    • Aitor Serres-Armero,
    • Brian W. Davis,
    • Inna S. Povolotskaya,
    • Carlos Morcillo-Suarez,
    • Jocelyn Plassais,
    • David Juan,
    • Elaine A. Ostrander,
    • and Tomas Marques-Bonet
    Genome Res. May 2021 31: 762-774; Published in Advance April 16, 2021, doi:10.1101/gr.266049.120
    ...these results.Finally, we highlight the importance of including multiomics data for conducting complete genetic analyses in any system, particularly those involving complex traits. The use of orthogonal genomic variants, such as tissue-specific lncRNA expression profiles, can help to contextualize the more...
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  5. Research: Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
    • Yumeng Wang,
    • Xiaoyan Xu,
    • Shuangxing Yu,
    • Kang Jin Jeong,
    • Zhicheng Zhou,
    • Leng Han,
    • Yiu Huen Tsang,
    • Jun Li,
    • Hu Chen,
    • Lingegowda S. Mangala,
    • Yuan Yuan,
    • A. Karina Eterovic,
    • Yiling Lu,
    • Anil K. Sood,
    • Kenneth L. Scott,
    • Gordon B. Mills,
    • and Han Liang
    Genome Res. July 2017 27: 1112-1125; Published in Advance April 14, 2017, doi:10.1101/gr.219741.116
    ...events alter the growthof cancer cells and also selectively change drug sensitivity in cell lines consistent with therapeutic relevance in patients. In addition to protein-coding genes, RNA editing can occur in noncoding genes, such as lncRNAs and microRNAs (miRNAs) (Gong et al. 2014, 2017).miRNAs are∼22...
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