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  1. ...-specific expression patterns in P. picta and P. parae strongly suggest the convergent evolution of a “Drosophila-likedosage compensation mechanism through a male-specific hyperexpression of the X Chromosome (Conrad and Akhtar 2012; Darolti et al. 2019; Metzger et al. 2021). Third, our study suggests convergent...
  2. ..., to study key features of biology and evolution in reptiles. We identify the rattlesnake Z Chromosome, including the recombining pseudoautosomal region, and find evidence for partial dosage compensation driven by an evolutionary accumulation of a female-biased up-regulation mechanism. Comparative analyses...
  3. ...finch revealed that the miRNA plays a role in dosage compensation of the bird Z Chromosome, by preferentially down-regulating Z-linked dosage-sensitive genes in males (Fig. 4). The need for dosage compensation arises during sex chromosome evolution when increasingly larger regions of the originally...
  4. ...) and Drosophila (Kaiser et al. 2011). Human X- and chicken Z-linked genes that show the strongest signatures of dosage compensation in either lineage also show signs of dosage sensitivity as measured by membership in large protein complexes (Pessia et al. 2012) or evolutionary patterns of gene duplication...
  5. ...Corresponding author: soojinyi@gatech.eduAbstractIn male heterogametic systems, the X Chromosome is epigenetically differentiated between males and females, to facilitate dosage compensation. For example, the X Chromosome in female mammals is largely inactivated. Relative to well-studied male heterogametic...
  6. ...was acquired before the divergence of Sauropsida (reptiles and birds) during the Paleozoic era. The amino acid sequence of Lyosin had undergone purifying selection although it was lost in some lineages, including the Neognathae birds and snakes. The Lyosin transcript was expressed in the testes of four...
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