Searching journal content for articles similar to Marbach et al. 22 (7): 1334.

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  1. ...in Drosophila melanogaster, much less is known about the origin and evolution of piCs in this or any other species. To investigate piC origin and evolution, we use a population genomic approach to compare piC activity and sequence composition across eight geographically distant strains of D. melanogaster...
  2. ...-derived sequences (Lipatov et al. 2005). A recent transcriptome-wide study identified 327 genes in Drosophila melanogaster that generate chimeric transcripts across different populations (Oliveira et al. 2023). Among all genes, 76 generate chimeric transcripts from TE insertions that were present in one strain...
  3. ...organism Encyclopedia of Regulatory Networks) consortia to systematically assay TF binding events in vivo in two major model organisms, Drosophila melanogaster (fly) and Caenorhabditis elegans (worm). These data sets comprise 605 TFs identifying 3.6 M sites in the fly and 356 TFs identifying 0.9 M sites...
  4. ..., interacting physiological systems. An increasing number of studies indicate that, beyond the traditionally emphasized hypothalamic–pituitary–gonadal (HPG) axis, metabolic and immune tissues are integral components of the regulatory network controlling laying performance. For instance, the liver sustains high...
  5. ...Transcriptional programs mediating neuronal toxicity and altered glial–neuronal signaling in a Drosophila knock-in tauopathy model Hassan Bukhari1,2, Vanitha Nithianandam1,2, Rachel A. Battaglia1,2, Anthony Cicalo2,3,4, Souvarish Sarkar1, Aram Comjean5, Yanhui Hu5, Matthew J. Leventhal6,7, Xianjun...
  6. ...are tightly controlled, raising the possibility that their breakdown products, tsRNAs, may provide a link between the overall translational status of a cell to specific changes in gene regulatory network. We hypothesize that Drosophila pupation, being a special developmental stage during which...
  7. ...and that (few) surviving transcripts gain stable and broader expressions, presumably via fast epigenetic control (Schmitz et al. 2020). Zhao et al. (2014) identified 106 de novo genes specifically expressed in the testis of laboratory strains of Drosophila melanogaster. Furthermore, Moyers and Zhang (2016...
  8. ...as covariation in their accessibility and transcription to infer functional links, termed cis-edges, in our networks. We define cis-edges as predicted regulatory relationships between REs and genes. For example, if GR binds a RE within a gene's promoter and induces gene activation, we draw a cis-edge between...
  9. ...in purifying selection pressure on regulatory networks important for brain function compared with liver function. One expectation from this hypothesis would be that TF binding motifs with a strong brain bias in TF binding would be depleted in TE sequences. To test this, we first inferred tissue bias in TF...
  10. ...target genes as identified by the ENCODE data set ENCSR407MOM, including HERC4, RIF1, TEAD1, and STAT5B (Subramanian et al. 2005; Sloan et al. 2016; Kolmykov et al. 2021). Although derived from Drosophila cells, this ChIP-seq data set has 2444 candidate target genes with human or primate orthologs...
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