Searching journal content for articles similar to Mallick et al. 19 (5): 922.

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  1. ...the accuracy of the detection of positive selection (Grossman et al. 2010).In this study, we investigated the genomic interplay between selection and genetic drift leading to the island syndrome in a system with an exceptionally long and clear history of population isolation. Common voles (Microtus arvalis...
  2. ...and genomic variation. Compared with demographic inference, this is more challenging, because studies of natural selection typically require larger sample sizes than studies of population history, which can integrate information from across the .Although some recent studies have used aDNA to study selection...
  3. ...nt. For example, the dot plot for the fourth genomic region of CHROMOSOME_X (122,781–250,556) is very dense and appears black owing to the high similarity between the 54-mers. In contrast, white areas indicate discordance. Regions are grouped by sequence similarity rather than their genomic position...
  4. ...encodes a real protein. Such filtering will be particularly important when an annotation method is known to produce many false-positive predictions, and yet, the choice of metrics and thresholds may be ad hoc. The best approach will likely involve selecting metrics and tuning thresholds to maximize...
  5. ...be explained by negative selection against long insertions in gene-dense genomic regions (Buckley et al. 2017; Ruggieri et al. 2022; Martelossi et al. 2024). Similarly to what was previously observed in the fungus Pleurotus ostreatus (Jacq.) P. Kumm. (Castanera et al. 2016), we found evidence of NAHR between...
  6. ...University, E-33600 Mieres, Spain; 8A.RE.NA, Asesores en Recursos Naturales, 27003 Lugo, Spain; 9University Museum, Norwegian University of Science and Technology, 7012 Trondheim, Norway; 10Centre for Ecological Genomics and Wildlife Conservation, Department of Zoology, University of Johannesburg, 2006 South...
  7. ...sequences were consistently depleted in highly brain-biased TF binding motif (Fig. 2G). One interpretation of these results may be that the evolutionary arms race between genomic “parasites” and the host results in selection pressure to “avoid” having sequences that function as, or can evolve into, CREs...
  8. ...strand of exons, suggesting that G4 structures on the nontranscribed strand are not maintained by natural selection. Thus, both stable and unstable G4s are unlikely to be functional, and stable G4s may be strongly avoided, in this group of genic components. Because such G4s can form at the level of RNA...
  9. ...(“Frame 2”) positions are shown. (C) Line plots depicting the distribution of mRNA exon lengths and the percent of mRNA exons at each length recovered by exon trapping. Plots have a 9 bp smoothing window applied. (D) Boxplots depicting GC content of trapped internal exons from different genomic regions. y...
  10. ...extensions infer the coalescence time of two homologous chromosomes at each genomic position. This inference is used in reconstructing demographic histories, detecting selection signatures, studying -wide associations, constructing ancestral recombination graphs, and more. Inference of coalescence times...
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